Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2013; 34(02): 104-106
DOI: 10.4103/0971-5851.116192
CASE REPORT

Subcutaneous panniculitis-like T-cell lymphoma in a case of carcinoma cervix

Meenakshi Swain
Department of Pathology, Apollo Hospitals, Jubilee Hills, Hyderabad, Andhra Pradesh, India
,
Gowrishankar Swarnalata
Department of Pathology, Apollo Hospitals, Jubilee Hills, Hyderabad, Andhra Pradesh, India
,
Trilok Bhandari
Department of Surgical Oncology, Apollo Hospitals, Jubilee Hills, Hyderabad, Andhra Pradesh, India
› Author Affiliations
› Further Information
Also available at
 PDF Download Permissions and Reprints

Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is an uncommon extra nodal non-Hodgkin lymphoma accounting for less than 1% of all NHLs known to have an aggressive course, with no well-defined treatment protocols. A 42-year-old lady, operated five months earlier for a squamous cell carcinoma of the cervix presented with pain and induration of the lower part of the anterior abdominal wall; 3 months after completing chemotherapy and radiotherapy. FNAC done, yielded scanty material and was inconclusive. The biopsy showed features of a subcutaneous panniculitis-like T-cell lymphoma. While on chemotherapy she developed a vault recurrence and extensive intra-abdominal spread of the squamous cell carcinoma and succumbed. SPTCL is a rare entity and has been reported in renal and cardiac allograft recipients and in one case of ovarian carcinoma. Its occurrence in the setting of carcinoma cervix is unusual, hence is being reported.

Keywords

Carcinoma cervix - panniculitis - T-cell lymphoma


Publication History

Article published online:
20 July 2021

© 2013. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Jaffe ES, Ralfkiaer E. Subcutaneous panniculitis-like T-cell lymphoma. In: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2001. p. 2120213.
  • 2 Chan JK. Tumours of the lymphoreticular system, including spleen and thymus. In: Fletcher CD, editor. Diagnostic Histopathology of Tumors. 2 nd ed.Philadelphia PA: Churchill Livingstone; 2000. p. 1182-83.
  • 3 Kaplan MA, Ferry JA, Harris NL, Jacobson JO. Clonal analysis of post transplant lymphoproliferative disorders, using both episomal Epstein - barr virus and immunoglobulin genes as markers. Am J Clin Pathol 1994;101:590-6.
  • 4 Eser B, Altuntas F, Er O, Kontas O, Ferahbas A, Cetin M, et al. A case of subcutaneous panniculitis-like T-cell lymphoma with haemophagocytosis developing secondary to chemotherapy. J Eur Acad Dermatol Venereol 2004;18:713-5.
  • 5 Arnulf B, Copie-Bergman C, Delfau-Larue MH, Lavergene-Slove A, Bosq J, Wechsler J, et al. Nonhepatosplenic gamma-delta T-cell lymphoma: A subset of cytotoxic lymphomas with mucosal or skin localization. Blood 1998;91:1723-31.
  • 6 Massone C, Chott A, Metze D, Kerl K, Citarella L, Vale E, et al. Subcutaneous blastic natural killer (NK), NK/T-cell and cytotoxic lymphomas of the skin: A morphologic immunophenotypic and molecular study of 50 patients. Am J Surg Pathol 2004:28:719-35.
  • 7 Salhany KE, Macon WR, Choi JK, Elenitsas R, Lession SR, Felgatr RE, et al. Subcutaneous panniculitis-like T-cell lymphoma: Clinicopathologic, immunophenotypic and genotypic analysis of alpha/beta and gamma/delta subtypes. Am J Surg Pathol 1998;22:881-93.
  • 8 Kumar S, Krenacs L, Medeiros J, Elenitoba - Johnson KS, Greiner TC, Sorbarabn L, et al. Subcutaneous panniculitis-like T-cell lymphoma is a tumour of cytotoxic T-lymphocytes. Hum Pathol 1998;29:397-403.
  • 9 Felgar RE, Macon WR, Kinney MC, Roberts S, Pasha T, Salhany KE. TIA - 1 expression in lymphoid neoplasms. Identifications of subsets with cytotoxic T-lymphocytes or natural killer cell differentiation. Am J Pathol 1997;150:1893-900.