L-asparaginase-induced cortical vein thrombosis in a child with leukemia: Can we rechallenge?

Arathi Srinivasan; Julius Xavier Scott; V Sivasubramanian

doi:10.4103/0971-5851.113437

Indian Journal of Medical and Paediatric Oncology, Table of Contents

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2013; 34(01): 51-52
DOI: 10.4103/0971-5851.113437

LETTERS TO EDITOR

L-asparaginase-induced cortical vein thrombosis in a child with leukemia: Can we rechallenge?

Arathi Srinivasan

Department of Pediatric Hemato Oncology, Kanchi Kamakoti CHILDS Trust Hospital and CHILDS Trust Medical Research Foundation, Chennai, Tamil Nadu, India

,

Julius Xavier Scott

Department of Pediatric Hemato Oncology, Kanchi Kamakoti CHILDS Trust Hospital and CHILDS Trust Medical Research Foundation, Chennai, Tamil Nadu, India

,

V Sivasubramanian

Department of Pediatric Hemato Oncology, Kanchi Kamakoti CHILDS Trust Hospital and CHILDS Trust Medical Research Foundation, Chennai, Tamil Nadu, India

› Author Affiliations

References
1 Athale UH, Chan AK. Thrombosis in children with acute lymphoblastic leukaemia: Epidemiology of thrombosis in children with acute lymphoblastic leukaemia. Thrombosis Res 2003;111:125-31.
2 Caruso V, lacoviello L, Castelnuovo AD, Storti S, Mariani G, de Gaetano G, et al. Thrombotic complications in childhood acute lymphoblastic leukemia: A meta-analysis of 17 prospective studies comprising 1752 pediatric patients. Blood 2006;108:2216-22.
3 Donati MB, Falanga A. Pathogenesis of thrombosis in cancer. Hematol J 2003;4:63-7.
4 Elhasid R, Lanir N, Sharon R, Weyl Ben Arush M, Levin C, Postovsky S, et al. Prophylactic therapy with enoxaparin during l-asparaginase treatment in children with acute lymphoblastic leukemia. Blood Coagul Fibrinolysis 2001;12:367-70.
5 Grace RF, Dahlberg SE, Neuberg D, Sallan SE, Connors JM, Neufeld EJ, et al. The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute consortium protocols. Br J Haematol 2011;152:452-9.