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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2013; 34(01): 28-30
DOI: 10.4103/0971-5851.113414
CASE REPORT

Candida albicans endocarditis in a child with acute lymphoblastic leukemia: A dreaded complication of intensive chemotherapy

Narendra Chaudhary
Department of Pediatrics, Pediatric Hematology Oncology Unit, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
,
Manini Vishwanath
Department of Pediatrics, Pediatric Hematology Oncology Unit, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
,
Mohit Pahuja
Department of Pediatrics, Pediatric Hematology Oncology Unit, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
,
Anupama Borker
Department of Pediatrics, Pediatric Hematology Oncology Unit, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
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Abstract

Candida endocarditis is a rare entity during febrile neutropenia due to early introduction of empirical antifungal therapy. Early surgical intervention has diagnostic and therapeutic importance in Candida endocarditis. We report a case of Candida albicans endocarditis in a child with acute lymphoblastic leukemia on chemotherapy. The role of surgical intervention is discussed.

Keywords

Acute lymphoblastic leukemia - chemotherapy - candida endocarditis


Publication History

Article published online:
20 July 2021

© 2013. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Frontera JA, Gradon JD. Right-side endocarditis in injection drug users: Review of proposed mechanisms of pathogenesis. Clin Infect Dis 2000;30:374-9.
  • 2 Habib G, Hoen B, Tornos P, Thuny F, Prendergast P, Vilacosta I, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009). Eur Heart J 2009;30:2369-413.
  • 3 Millar BC, Moore JE. Current trends in the molecular diagnosis of infective endocarditis. Eur J Clin Microbiol Infect Dis 2004;23:353-65.
  • 4 Pappas PG, Kauffman CA, Andes D, Benjamin DK, Calandra TF, Edwards JE, et al. Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America. Clin Inf Dis 2009;48:503-35.
  • 5 Steinbach WJ, Perfect JR, Cabell CH, Fowler VG, Corey GR, Li JS, et al. A meta-analysis of medical versus surgical therapy for Candida endocarditis. J Infect 2005;51:230-47.
  • 6 Ellis ME, Al-Abdely H, Sandridge A, Greer W, Ventura W. Fungal Endocarditis: Evidence in the World Literature, 1965-1995. Clin Inf Dis 2001;32:50-62.
  • 7 Talarmin JP, Boutoille D, Tattevin P, Abgueguen P, Ansart S, Roblot F, et al. Candida endocarditis: Role of new antifungal agents. Mycoses 2008;52:60-6.
  • 8 Falcone M, Barzaghi N, Carosi G, Grossi P, Minoli L, Ravasio V, et al. for the Italian Study on Endocarditis (ISE). Candida infective endocarditis: Report of 15 cases from a prospective multicenter study. Medicine 2009;88:160-8.
  • 9 David TE, Gavra G, Feindel CM, Regesta T, Armstrong S, Maganti MD. Surgical treatment of active infective endocarditis: A continued challenge. J Thorac Cardiovasc Surg 2007;133:144-9.
  • 10 Martin-Davila P, Navas E, Fortun J, Moya JL, Cobo J, Pintado V, et al. Analysis of mortality and risk factors associated with native valve endocarditis in drug users: The importance of vegetation size. Am Heart J 2005;150:1099-106.