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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2012; 33(03): 176-178
DOI: 10.4103/0971-5851.103148
CASE REPORT

Uterine smooth muscle tumor of uncertain malignant potential: A rare cause of multiple pulmonary nodules

Ioannis C Kotsopoulos
Department of Gynecologic Oncology, Theagenio Cancer Hospital, Thessaloniki, Greece
,
Nikolaos Barbetakis
Department of Thoracic Surgery, Theagenio Cancer Hospital, Thessaloniki, Greece
,
Christos G Asteriou
Department of Thoracic Surgery, Theagenio Cancer Hospital, Thessaloniki, Greece
,
Markos Voutsas
Department of Histopathology, Theagenio Cancer Hospital, Thessaloniki, Greece
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Abstract

Smooth muscle tumors of uncertain malignant potential (STUMP) are mesenchymal uterine tumors lying between benign leiomyomas and leiomyosarcomas. Although lung metastases from uterine leiomyosarcoma are common, ′′STUMP′′ usually does not metastasize. A case of a 51-year-old woman with progressive dyspnea on exertion and multiple space-occupying lesions in both lungs is presented. She had a history of a total abdominal hysterectomy 3 years ago. Lung biopsy through video-assisted thoracic surgery was consistent with metastatic malignant smooth muscle cell tumor. She received multiple cycles of chemotherapy and died 11 months later. Cell necrosis, atypia and mitotic count are important criteria determining the malignant potential of a uterine smooth muscle tumor. The diagnosis and clinical course of STUMP are not totally and clearly known, and metastasis, especially pulmonary with pleural effusion, is not a common phenomenon. When this occurs, prognosis seems to be poor. Surveillance of these patients should be close and long term.

Keywords

Leiomyoma - leiomyosarcoma - lung - metastasis - uterus


Publication History

Article published online:
02 August 2021

© 2012. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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