Download PDF
CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2005; 15(02): 233-238
DOI: 10.4103/0971-3026.28812
Original Article

Changing pattern of bronchogenic carcinoma : A statistical variation or a reality?

CM Shetty
Department of Radio diagnosis & Imaging, Kasturba Medical College and Hospital, Manipal-576104, Karnataka, India
,
BN Lakhkar
Department of Radio diagnosis & Imaging, Kasturba Medical College and Hospital, Manipal-576104, Karnataka, India
,
VSS Gangadhar
Department of Radio diagnosis & Imaging, Kasturba Medical College and Hospital, Manipal-576104, Karnataka, India
,
NR Ramachandran
Department of Radio diagnosis & Imaging, Kasturba Medical College and Hospital, Manipal-576104, Karnataka, India
› Author Affiliations
› Further Information
  PDF Download Permissions and Reprints

Abstract

OBJECTIVES: To document the various CT appearances of bronchogenic carcinoma with histopathologic correlation, to identify changing trend in the radiographic pattern of bronchogenic carcinoma, if any and to evaluate the role of CT in staging of bronchogenic carcinoma was also evaluated. MATERIALS AND METHODS A prospective study of 81 patients over a period of 2 yrs with clinical and or radiological suspicion of bronchogenic carcinoma and confirmed histopathogical diagnosis was undertaken with CT of the thorax using 10 mm collimation sections from the level of lung apices to the diaphragm and routinely included the adrenals. RESULTS : Squamous cell carcinoma is the most common histologic subtype followed by adenocarcinoma and small cell carcinoma. There was a definite male preponderance with smoking being the most common risk factor. Adenocarcinoma is presenting predominantly as central tumor( 70.5% ) Squamous cell carcinoma is presenting predominantly as peripheral tumor (52.7% ) . CONCLUSION Computed tomography is the modality of choice for evaluating bronchogenic carcinoma because of its better spatial resolution. CT provides precise characterization of the size, contour, extent and tissue composition of the suspicious lesion. If the lesion represents a bronchogenic carcinoma, CT serves as a part of the staging process to assess the extent of the disease. The radiologic presentation of adenocarcinoma and squamous cell carcinoma is showing a changing pattern. In our study, adenocarcinoma is presenting predominantly as a central tumor and Squamous cell carcinoma is presenting predominantly as a peripheral tumor. This relative increase in the percentage of centrally located adenocarcinoma is a statistical variation or a reality needs to be evaluated further.

Keywords

CT - bronchogenic carcinoma


Publication History

Article published online:
31 July 2021

© 2005. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

  • References

  • 1 Gupta RC, Purohit SD, Sharma MP, Bhardwaj S. Primary bronchogenic carcinoma : clinical profile of 279 cases from mid west Rajasthan .Indian Chest Allied Sciences 1998 ; 40 : 109-116.
  • 2 Chhajed PN, Athavale AU, Shah AC . Clinical and pathological profile in patients with lung carcinoma : Is the picture changing ? JAPI 1999 ; 47 : 483 - 487.
  • 3 Woodring JH, Stelling CB. Adenocarcinoma of the lung : A tumor with a changing pleomorphic character. AJR 1983 ; 140 : 657-664.
  • 4 Sharma CP, Behara D , Aggarawal AN , Gupta D, Jindal SK. Radiographic patterns in lung cancer .Indian J Chest Dis Allied Sci 2002 ; 44: 25-30.
  • 5 Quinn D,Gianlupi A,Broste S. The changing radiographic presentation of bronchogenic carcinoma with reference to cell types. Chest 1996 ;110 : 1474.
  • 6 Murray JF, Nadel JA .Textbook of Respiratory medicine.3rd ed. Philadelphia. W.B.Saunders; 2000: 1385.
  • 7 Pass IH, Mitchell JB, Johnson DH. Lung cancer .Principles and practice.2nd edition.Philadelphia.Lippincott Williams and Wilkins;2000.
  • 8 Jain NK, Madan A , Sharma TN, etal. A study of 109 cases of bronchogenic carcinoma .JAPI 1989 ; 37: 379-82.
  • 9 Guleria JS, Gopinath N, Talwar JR etal. Bronchial carcinoma : An analysis of 120 cases. JAPI 1971 ; 19 : 251-55.
  • 10 Jain NK, Madan A , Sharma TN, etal. A study of 109 cases of bronchogenic carcinoma . JAPI 1989 ; 37: 379-82.