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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2015; 25(02): 121-128
DOI: 10.4103/0971-3026.155835
Imaging in Oncology: Recent Advances

Imaging for assessment of treatment response in hepatocellular carcinoma: Current update

Koichi Hayano
Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
,
Sang Ho Lee
Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
,
Dushyant V Sahani
Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA
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Abstract

Morphologic methods such as the Response Evaluation Criteria in Solid Tumors (RECIST) are considered as the gold standard for response assessment in the management of cancer. However, with the increasing clinical use of antineoplastic cytostatic agents and locoregional interventional therapies in hepatocellular carcinoma (HCC), conventional morphologic methods are confronting limitations in response assessment. Thus, there is an increasing interest in new imaging methods for response assessment, which can evaluate tumor biology such as vascular physiology, fibrosis, necrosis, and metabolism. In this review, we discuss various novel imaging methods for response assessment and compare them with the conventional ones in HCC.

Keywords

Computed tomography perfusion - diffusion weighted imaging - amic contrast-enhanced magnetic resonance imaging - hepatocellular carcinoma - positron emission tomography


Publication History

Article published online:
30 July 2021

© 2015. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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