Open Access
CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2014; 24(04): 350-359
DOI: 10.4103/0971-3026.143897
Transplant Imaging

Preoperative CT evaluation of potential donors in living donor liver transplantation

Sandeep Vohra
Department of Radiology, Center for Liver and Biliary Sciences, Indraprastha Apollo Hospital, New Delhi, India
,
Neerav Goyal
Departments of Surgical Gastroenterology and Liver Transplant, Center for Liver and Biliary Sciences, Indraprastha Apollo Hospital, New Delhi, India
,
Subash Gupta
Departments of Surgical Gastroenterology and Liver Transplant, Center for Liver and Biliary Sciences, Indraprastha Apollo Hospital, New Delhi, India
› Author Affiliations
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Abstract

Living donor liver transplantation is an effective, life sustaining surgical treatment in patients with end-stage liver disease and a successful liver transplant requires a close working relationship between the radiologist and the transplant surgeon. There is extreme variability in hepatic vascular anatomy; therefore, preoperative imaging of potential liver donors is crucial not only in donor selection but also helps the surgeons in planning their surgical approach. In this article, we elaborate important aspects in evaluation of potential liver donors on multi-detector computed tomography (MDCT) and the utility of MDCT in presurgical assessment of the hepatic parenchyma, relevant hepatic vascular anatomy and segmental liver volumes.



Publication History

Article published online:
02 August 2021

© 2014. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Erbay N, Raptopoulos V, Pomfret EA, Kamel IR, Kruskal JB. Living donor liver transplantation in adults: Vascular variants important in surgical l planning for donors and recipients. AJR Am J Roentgenol 2003;181:109-14.
  • 2 Inomato Y, Uemoto S, Asonuma K, Egawa H. Right lobe graft in living donor liver transplantation. Transplantation 2000;69:258-64.
  • 3 Ioannou GN. Development and validation of a model predicting graft survival after liver transplantation. Liver Transpl 2006;12:1594-606.
  • 4 Singh AK, Cronin CG, Verma HA, Boland GW, Saini S, Mueller PR, et al. Imaging of preoperative liver transplantation in adults: What radiologist should know. Radiographics 2011;31:1017-30.
  • 5 Schroeder T, Radtke A, Kuehl H, Debatin JF, Malagó M, Ruehm SG. Evaluation of living liver donors with an all-inclusive 3D multi-detector row CT protocol. Radiology 2006;238:900-10.
  • 6 Mortelé KJ, Cantisani V, Troisi R, de Hemptinne B, Silverman SG. Preoperative liver donor evaluation: Imaging and pitfalls. Liver Transpl 2003;9:S6-14.
  • 7 Alonso-Torres A, Fernández-Cuadrado J, Pinilla I, Parrón M, de Vicente E, López-Santamaría M. Multidetector CT in the evaluation of potential living donors for liver transplantation. Radiographics 2005;25:1017-30.
  • 8 Strasberg SM, Belghiti J, Clavien PA, Gadzijev E, Garden JO, Lau WY, et al. The Brisbane 2000 terminology of liver anatomy and resection. Terminology committee of the International Hepato-Pancreatico-Biliary Association. HPB 2000;2:333-9.
  • 9 Michalopoulos GK. Liver regeneration. J Cell Physiol 2007;213:286-300.
  • 10 Tanaka K, Yamada T. Living donor liver transplantation in Japan and Kyoto University: What can we learn? J Hepatol 2005;42:25-8.
  • 11 Catalano OA, Singh AH, Uppot RN, Hahn PF, Ferrone CR, Sahani DV. Vascular and biliary variants in the liver: Implications for liver surgery. Radiographics 2008;28:359-78.
  • 12 Zhuang ZG, Qian LJ, Gong HX, Zhou Y, Chai WM, Li QG, et al. Multidetector computed tomography angiography in the evaluation of potential living donors for liver transplantation: Single-center experience in China. Transplant Proc 2008;40:2466-77.
  • 13 Caruso S, Miraglia R, Maruzzelli L, Gruttadauria S, Luca A, Gridelli B. Imaging in liver transplantation. World J Gastroenterol 2009;15:675-83.
  • 14 Kodama Y, Ng CS, Wu TT, Ayers GD, Curley SA, Abdalla EK, et al. Comparison of CT methods for determining the fat content of the liver. AJR Am J Roentgenol 2007;188:1307-12.
  • 15 Lee SW, Park SH, Kim KW, Choi EK, Shin YM, Kim PN, et al. Unenhanced CT for assessment of macrovesicular hepatic steatosis in living liver donors: Comparison of visual grading with liver attenuation index. Radiology 2007;244:479-85.
  • 16 Ma X, Holalkere NS, Kambadakone RA, Mino-Kenudson M, Hahn PF, Sahani DV. Imaging-based quantification of hepatic fat: Methods and clinical applications. Radiographics 2009;29:1253-77.
  • 17 Limanond P, Raman SS, Lassman C, Sayre J, Ghobrial RM, Busuttil RW, et al. Macrovesicular hepatic steatosis in living related liver donors: Correlation between CT and histologic findings. Radiology 2004;230:276-80.
  • 18 Brancatelli G. Science to practice: Should biopsy be performed in potential liver donors when unenhanced CT shows an unacceptable degree of steatosis for transplantation? Radiology 2006;239:1-2.
  • 19 Pannu HK, Maley WR, Fishman EK. Liver transplantation: Preoperative CT evaluation. Radiographics 2001;21 Spec No: S133-46.
  • 20 Michels NA. Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg 1966;112:337-47.
  • 21 Lee SY, Cherqui D, Kluger MD. Extended right hepatectomy in a liver with a non-bifurcating portal vein: The hanging maneuver protects the portal system in the presence of anomalies. J Gastrointest Surg 2013;13:1494-9.
  • 22 Nakamura T, Tanaka K, Kiuchi T, Kashara M, Oike F, Ueda M, et al. Anatomical variants and surgical strategies in right lobe liver donor liver transplantation: Lessons from 120 cases. Transplantation 2002;73:1896-903.
  • 23 Sahani D, Mehta A, Blake M, Prasad S, Harris G, Saini S. Preoperative hepatic vascular evaluation with CT and MR angiography: Implications for surgery. Radiographics 2004;24:1367-80.
  • 24 Marcos A, Orloff M, Mieles L, Olzinski AT, Renz JF, Sitzmann JV. Functional venous anatomy for right-lobe grafting and techniques to optimize outflow. Liver Transpl 2001;7:845-52.
  • 25 Wang F, Pan KT, Chu SY, Chan KM, Chou HS, Wu TJ, et al. Preoperative estimation of the liver graft weight in adult right lobe living donor liver transplantation using maximal portal vein diameters. Liver Transpl 2011;17:373-80.
  • 26 Kim KW, Lee J, Lee H, Jeong WK, Won HJ, Shin YM, et al. Right lobe estimated blood-free weight for liver transplantation: Accuracy of automated blood-free CT volumetry--preliminary results. Radiology 2010;256:433-40.
  • 27 Luciani A, Rusko L, Baranes L, Pichon E, Loze B, Deux JF, et al. Automated liver volumetry in orthotopic liver transplantation using multiphase acquisitions on MDCT. AJR Am J Roentgenol 2012;198:W568-74.
  • 28 Nakayama Y, Li O, Katsurgawa S, Ikeda R, Hiai Y, Awai K, et al. Automated hepatic volumetry for living related liver transplantation at multisection CT. Radiology 2006;240:743-8.
  • 29 Hsu SL, Chen TY, Huang TL, Sun CK, Concejero AM, Tsang LL, et al. Left-sided gall bladder: Its clinical significance and imaging presentations. World J Gastroenterol 2007;13:6404-9.