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J Am Acad Audiol 2019; 30(06): 493-501
DOI: 10.3766/jaaa.17123
Articles
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Hormones and Hearing: Central Auditory Processing in Women

Skylar Trott
*   University of Kentucky College of Medicine, Lexington, KY
,
Trey Cline
†   Department of Otolaryngology-Head and Neck Surgery, University of Kentucky, Lexington, KY
,
Jeffrey Weihing
‡   Department of Audiology, University of Louisville, Louisville, KY
,
Deidra Beshear
§   Divisions of Women’s Health, Department of Internal Medicine, University of Kentucky, Lexington, KY
,
Matthew Bush
†   Department of Otolaryngology-Head and Neck Surgery, University of Kentucky, Lexington, KY
,
Jennifer Shinn
†   Department of Otolaryngology-Head and Neck Surgery, University of Kentucky, Lexington, KY
› Author Affiliations
Further Information

Publication History

06 February 2018

13 March 2018

Publication Date:
25 May 2020 (online)

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Abstract

Background:

Estrogen has been identified as playing a key role in many organ systems. Recently, estrogen has been found to be produced in the human brain and is believed contribute to central auditory processing. After menopause, a low estrogen state, many women report hearing loss but demonstrate no deficits in peripheral hearing sensitivity, which support the notion that estrogen plays an effect on central auditory processing. Although animal research on estrogen and hearing loss is extensive, there is little in the literature on the human model.

Purpose:

The aim of this study was to evaluate relationships between hormonal changes and hearing as it relates to higher auditory function in pre- and postmenopausal (Post-M) females.

Research Design:

A prospective, group comparison study.

Study Sample:

Twenty eight women between the ages of 18 and 70 at the University of Kentucky were recruited.

Data Collection and Analysis:

Participants were separated into premenopausal and peri-/Post-M groups. Participants had normal peripheral hearing sensitivity and underwent a behavioral auditory processing battery and electrophysiological evaluation. An analysis of variance was performed to address the aims of the study.

Results:

Results from the study demonstrated statistically significant difference between groups, where Post-M females had difficulties in spatial hearing abilities as reflected on the Listening in Spatialized Noise Test–Sentences test. In addition, measures on the auditory brainstem response and the middle latency response reflected statistically significant differences between groups with Post-M females having longer latencies.

Conclusions:

Results from the present study demonstrated significant differences between groups, particularly listening in noise. Females who present with auditory complaints in spite of normal hearing thresholds should have a more extensive audiological evaluation to further evaluate possible central deficits.

Key Words

central auditory processing disorder - menopause
 

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