J Am Acad Audiol 2004; 15(04): 324-333
DOI: 10.3766/jaaa.15.4.6
American Academy of Audiology. All rights reserved. (2004) American Academy of Audiology

Functional and Anatomical Correlates of Impaired Velocity Storage

Gary P. Jacobson
Devin L. McCaslin
Suresh Patel
Kamrin Barin
Nabih M. Ramadan
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Publication Date:
07 August 2020 (online)

Velocity storage (VS), a brainstem function, extends the low-frequency response of the vestibular system. To better understand VS mechanisms and characteristics in humans, we analyzed retrospectively functional measures of gait, electrophysiological measures of vestibular function, and imaging studies in an attempt to determine clinical, electrophysiological, and anatomical correlates of abnormalities in VS.

Two cohorts of patients referred to our Risk of Falls Assessment Clinic participated in this investigation. Group 1 (control) patients demonstrated normal caloric and rotary chair tests. Group 2 patients with impaired velocity storage (experimentals) differed clinically from Group 1 only by demonstrating abnormal multifrequency vestibulocular reflex phase measures on rotational testing.

Results showed that Group 2 patients had greater impairments in postural stability and gait than Group 1 patients. Additionally, 80% of patients in Group 2 and none in Group 1 showed pontine hyperintense lesions on MRI.