Vet Comp Orthop Traumatol 2010; 23(01): 56-61
DOI: 10.3415/VCOT-09-02-0016
Clinical Communication
Schattauer GmbH

Nutritional secondary hyperparathyroidism in two cats

Evaluation of bone mineral density with dual-energy X-ray absorptiometry and computed tomography
M. Dimopoulou
1   Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen
,
J. Kirpensteijn
1   Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen
3   Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands
,
D. H. Nielsen
1   Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen
,
L. Buelund
1   Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen
,
M. S. Hansen
2   Veterinary Pathobiology Faculty of Life Sciences, University of Copenhagen
› Author Affiliations
Further Information

Publication History

Received: 09 February 2009

Accepted: 10 July 2009

Publication Date:
19 December 2017 (online)

Summary

Two three-month-old, intact female Abyssinian cats were presented with a history of lameness, constipation and ataxia. The cats had been fed a diet composed almost exclusively of meat. Both showed severe osteopenia and multiple pathological fractures on radiography. Following euthanasia of the more severely affected cat, postmortem examination revealed changes consistent with nutritional secondary hyperparathyroidism and fibrous osteodystrophy, such as cortical thinning, massive connective tissue invasion in the diaphysis of long bones, and hypertrophy of the chief cells in both parathyroid glands. After introducing a balanced commercial diet to the surviving cat, bone mineralisation improved from the baseline value, and at subsequent examinations at three, six and 22 weeks later, as indicated by bone mineral density measurements obtained by dual-energy X-ray absorptiometry and computed tomography.