Histiocytic sarcoma of the stifle in a dog with cranial cruciate ligament failure and TPLO treatment

Summary

A 10-year-old spayed female Golden Retriever was admitted with chronic lameness of the right hind limb. A tibial plateau leveling osteotomy (TPLO) had been performed on this leg approximately three years previously. A progressively growing soft tissue mass, affecting the right stifle, previously treated with TPLO was biopsied and found to be a histiocytic sarcoma. Previously proposed links between the development of neoplasia in the stifle region and the presence of chronic synovitis, osteotomy, orthopaedic implants, and specifically the Slocum TPLO plate, are briefly discussed.

Keywords

Histiocytic sarcoma - TPLO

• References

• 1 Bass M, Gardelle O, Grest P. et al. Localized histiocytic sarcoma in a dog: an uncommon diagnosis in forelimb lameness.. Vet Comp Orthop Traumatol 2006; 1: 48-52.
• 2 Boudrieau RJ, McCarthy RJ, Sisson RD. Jr. Sarcoma of the proximal portion of the tibia in a dog 5.5 years after tibial plateau leveling osteotomy.. J Am Vet Med Assoc 2005; 227: 1613-1617 1591.
• 3 Craig LE, Julian ME, Ferracone JD. The diagnosis and prognosis of synovial tumors in dogs: 35 cases.. Vet Pathol 2002; 39: 66-73.
• 4 Dubielzig RR, Biery DN, Brodey RS. Bone sarcomas associated with multifocal medullary bone infarction in dogs.. J Am Vet Med Assoc 1981; 179: 64-68.
• 5 Pool RR, Thompson KG. Tumors of joints. In: Tumors in domestic animals. ed. Meuten DJ, 04. th ed 199-317. Iowa State Press, Ames, 2002
• 6 Riser WH, Brodey RS, Biery DN. Bone infarctions associated with malignant bone tumors in dogs.. J Am Vet Med Assoc 1972; 160: 414-421.
• 7 Stevenson S. Fracture-associated sarcomas.. Vet Clin North Am Small Anim Pract 1991; 21: 859-872.
• 8 Stevenson S, Hohn RB, Pohler OE. et al. Fracture-associated sarcoma in the dog.. J Am Vet Med Assoc 1982; 180: 1189-1196.
• 9 Straw M. What is your diagnosis? Synovial sarcoma.. Vet Clin Pathol 2005; 46: 457-459.