Pulmonary arteriovenous malformations may result in intrapulmonary shunting and hypoxemia,
and often are treated by embolization or surgical resection. Previous reports have
demonstrated effective treatment of hypoxia with inhaled nitric oxide in the acute
setting. In this report, we describe a child with severe hypoxemia secondary to an
inoperable pulmonary arteriovenous malformation that was initially managed with the
use of nitric oxide followed by long term management with the phosphodiesterase-5
inhibitor, sildenafil.
Keywords
Arteriovenous malformations - nitric oxide - phosphodiesterase-5 inhibitors
