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Journal of Pediatric Epilepsy 2013; 02(01): 033-048
DOI: 10.3233/PEP-13046
Review Article
Georg Thieme Verlag KG Stuttgart – New York

The use of MRS in the evaluation of pediatric epilepsy

Paul A. Caruso
a   Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
,
Jason Johnson
a   Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
,
Ron Thibert
b   Epilepsy Service, Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
,
Otto Rapalino
a   Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
,
Sandra Rincon
a   Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
,
Eva-Maria Ratai
a   Division of Neuroradiology, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
c   Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
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Publication History

08 July 2013

11 July 2013

Publication Date:
17 July 2015 (online)

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Abstract

This chapter is a practical “why, how to, and when” chapter, written in three parts to address three questions that arise when the epileptologist or neuroimager evaluates a patient with epilepsy. Why do magnetic resonance spectroscopy (MRS)? How to do MRS in the patient with epilepsy? When, that is, in what clinical-imaging setting, can MRS help to diagnose or manage the patient with epilepsy?

Keywords

MRI - MRS - epilepsy - inborn error of metabolism - malformation of cortical development - focal cortical dysplasia - tumor - neoplasm