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Journal of Pediatric Neurology 2012; 10(03): 225-227
DOI: 10.3233/JPN-2012-0568
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Secondary parkinsonism with bilateral involvement of substantia nigra in cerebral malaria

Authors

  • Hanene Benrhouma

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

  • Youssef Sidhom

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

  • Aida Rouissi

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

  • Sonia Nagi

    b   Department of Neuroradiology, National Institute of Neurology, Tunis, Tunisia

  • Ichraf Kraoua

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

  • Jihene Yacoubi

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

  • Mohamed Ben Hammouda

    b   Department of Neuroradiology, National Institute of Neurology, Tunis, Tunisia

  • Neziha Gouider-Khouja

    a   Department of Child and Adolescent Neurology, National Institute of Neurology, Tunis, Tunisia

Subject Editor:
Further Information

Publication History

25 January 2012

29 February 2012

Publication Date:
30 July 2015 (online)

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Abstract

Cerebral malaria is characterized by various non-specific neurologic features with usually diffuse cerebral edema on magnetic resonance imaging. We report on an exceptional case of cerebral malaria with isolated parkinsonism and bilateral substantia nigra involvement. We discuss the pathophysiology leading to involvement of substantia nigra and treatment options.

Keywords

Cerebral malaria - parkinsonism - substantia nigra