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Journal of Pediatric Neurology 2011; 09(04): 497-500
DOI: 10.3233/JPN-2012-0516
Georg Thieme Verlag KG Stuttgart – New York

Thrombolysis with rt-PA for an ischemic stroke in boy treated with Fontan operation

Mariangela Bianco
a   Department of Neurology, San Raffaele Hospital, Milan, Italy
,
Franco Simionato
b   Department of Pediatric Neuroradiology, San Raffaele Hospital, Milan, Italy
,
Cristina Giusti
a   Department of Neurology, San Raffaele Hospital, Milan, Italy
,
Francesco Corea
c   Department of Rehabilitation, San Giovanni Battista Hospital, Foligno, Italy
,
Alessandra Giua
d   Department of Neurology, University of Sassari, Sassari, Italy
,
Vittorio Martinelli
a   Department of Neurology, San Raffaele Hospital, Milan, Italy
,
Giancarlo Comi
a   Department of Neurology, San Raffaele Hospital, Milan, Italy
,
Maria Sessa
a   Department of Neurology, San Raffaele Hospital, Milan, Italy
› Author Affiliations
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Further Information

Publication History

16 February 2010

03 January 2011

Publication Date:
30 July 2015 (online)

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Abstract

We first report the case of a 14-year-old boy, previously treated with a modified Fontan operation at the age of 2, who underwent an intra-arterial thrombolysis for an ischemic stroke with a favorable outcome. No controlled randomized trials on thrombolysis among childhood stroke have been conducted yet. This and other similar cases suggest that thrombolysis may also be safe and beneficial in pediatric patients and those cases may benefit from a prompt access to specialized stroke centers.

Keywords

Ischemic stroke - Fontan operation - thrombolysis - recombinant tissue plasminogen activator