Journal of Pediatric Neurology 2010; 08(04): 403-406
DOI: 10.3233/JPN-2010-0422
Georg Thieme Verlag KG Stuttgart – New York

Cerebral sinovenous thrombosis in a child with ulcerative colitis: A case report

Authors

  • Nahin Hussain

    a   Department of Pediatric Neurology, Children's Hospital, Leicester Royal Infirmary, University Hospital of Leicester NHS Trust, Leicester, UK
  • Arun Pugalenthi

    a   Department of Pediatric Neurology, Children's Hospital, Leicester Royal Infirmary, University Hospital of Leicester NHS Trust, Leicester, UK
  • Jayaprakash Gosalakkal

    a   Department of Pediatric Neurology, Children's Hospital, Leicester Royal Infirmary, University Hospital of Leicester NHS Trust, Leicester, UK

Subject Editor:
Further Information

Publication History

02 September 2008

22 July 2009

Publication Date:
30 July 2015 (online)

Abstract

Cerebral sinovenous thrombosis (CSVT) is a rare and under-diagnosed complication of ulcerative colitis. We report a case of a 14-year-old male child, who presented with a history of worsening headaches, vomiting and decreased level of consciousness. He was diagnosed to have CSVT with infarction on magnetic resonance imaging of the brain. He was treated with low molecular weight heparin and discharged home with a mild right-sided hemiparesis. At a year follow-up, his neurological examination was normal. The use of antithrombotic therapy, in particular low molecular weight heparin can be effective in reducing the mortality and morbidity associated with CSVT. Nevertheless, randomized placebo-controlled studies are necessary for assessing its efficacy and absence of risk in children.