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J Pediatr Infect Dis 2011; 06(01): 045-049
DOI: 10.3233/JPI-2011-0284
Georg Thieme Verlag KG Stuttgart – New York

A HIV-infected adolescent with polycystic ovary syndrome

Prapai Dejkhamron
a   Department of Pediatrics, Division of Endocrinology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
,
Kevalee Unachak
a   Department of Pediatrics, Division of Endocrinology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
,
Manik Chhabra
b   Department of Medicine, University of Minnesota, Minneapolis, MN, USA
,
Peninnah Oberdorfer
c   Department of Pediatrics, Division of Infectious Diseases, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
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Further Information

Publication History

12 March 2010

23 August 2010

Publication Date:
28 July 2015 (online)

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Abstract

We report a case of polycystic ovary syndrome in a 15-year-old human immunodeficiency virus-infected female on highly active antiretroviral therapy who developed hypertriglyceridemia, hyperinsulinemia due to insulin resistance, and hyperandrogenism. Ultrasonography showed multiple small follicles at the right ovary and lobulated follicles at the left ovary. Treatment of polycystic ovary syndrome included insulin sensitizing agents (metformin, pioglitazone) and a contraceptive for hyperandrogenism. We also encouraged life style modification including regular exercise and dietary fat restriction. She attained menarche 1 month after initiation of treatment.

Keywords

PCOS - HIV - HAART