An 801 gram very premature infant was delivered by Cesarian section at 28 weeks gestation
and developed invasive Candida parapsilosis infection at 4 weeks of age complicated with obstructive uropathy, bilateral hydronephrosis
and bladder fungus ball. The baby was treated with systemic amphotericin B and bladder
irrigation with amphotericin B solution. Treatment resulted in complete eradication
of the bladder fungus ball and resolution of the obstructive uropathy. The difficulty
of performing bladder irrigation in an extremely small premature infant is discussed.
This case illustrates the need to investigate for renal involvement in newborns with
persistent candidemia and the effectiveness of bladder irrigation with amphotericin
B solution in the treatment of bladder fungus balls.
Keywords
Bladder fungus ball - neonate - candidiasis
