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Arquivos Internacionais de Otorrinolaringologia 2011; 15(01): 102-105
DOI: 10.1590/S1809-48722011000100017
Case Report
Thieme Publicações Ltda Rio de Janeiro, Brazil

Nasosinusal Lymphoma of T Natural Killer Cells: Case Report

Linfoma Nasossinusal de Células T Natural Killer: Relato de Caso
Victor Labres da Silva Castro
*   Resident Physician in Otorhinolaryngology.
,
João Batista Ferreira
**   Postdoctoral Degree in Otorhinolaryngology. Assistant Professor of the Surgery Department of the Medical School - UFG. Chief of the Otorhinolaryngology Clinic of the Clinical Hospital - UFG.
,
Valeriana de Castro Guimarães
***   In course for Doctoral Degree in Health Sciences UFG. Phonoaudiologist of the Clinical Hospital - UFG.
,
Gustavo Vasconcelos Nery
****   Otorhinolaryngologist of the Clinical Hospital - UFG.
,
Tiago Fernando Côrrea Aires
*****   Resident Physician in Otorhinolaryngology of the Clinical Hospital - UFG.
,
Wilder Alves
****   Otorhinolaryngologist of the Clinical Hospital - UFG.
› Author Affiliations
Further Information

Publication History

16 June 2009

12 July 2009

Publication Date:
12 February 2014 (online)

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Summary

Introduction: The primary nasal lymphoma is an uncommon extranodal tumor and represents 0.44% of all Extranodal lymphomas in this region. The primary nasal lymphoma derives from the T-lineage in nearly 75% of the cases.

Objective: To describe a case of nasosinusal lymphoma of T Natural Killer cells, attended in the Clinical Hospital of the Federal University of Goiás.

Case Report: 48-year-old female patient with diffuse tumefaction in the left hemiface of firm-elastic consistency and painful upon digital compression. Face sinuses tomography identified a total maxillary veiling to the left and some posterior ethmoidal cells. With the diagnostic hypothesis of a tumor affection, we opted for the surgical removal via a transmaxillary approach and the material was sent for biopsy. The histopathological exam diagnosed a highly necrotic tumor of angiocentric pattern, polymorphic and atypical lymphoid population (T /NK Lymphoma); with the prognosis, the patient was submitted to chemical therapy with total regression of the facial edema.

Final Comments: The otorhinolaryngologist must be attentive as regards the existence of lymphomas among the nasosinusal diseases, because the early diagnosis improves the survival as it prevents metastases, growth and local destruction.

Resumo

Introdução: O linfoma nasal primário é um tumor extranodal raro e representa 0,44% de todos os linfomas extranodais nessa localização. O linfoma nasal primário deriva da linhagem T em torno de 75% dos casos.

Objetivo:Descrever um caso de Linfoma nasossinusal de células T Natural Killer, atendido no Hospital das Clínicas da Universidade Federal de Goiás.

Relato do Caso: Paciente de 48 anos, sexo feminino, apresentando tumefação difusa na hemiface esquerda, de consistência firme-elástica e dolorosa a compressão digital. Tomografia dos seios da face identificou um velamento maxilar total à esquerda e de algumas células etmoidais posteriores. Com a hipótese diagnóstica de uma afecção tumoral, optou-se por remoção cirúrgica via transmaxilar, sendo encaminhado o material para biopsia. O exame histopatológico diagnosticou um tumor altamente necrótico padrão angiocêntrico, população linfoide polimórfica e atípica (Linfoma T/NK), diante do diagnóstico a paciente foi submetida à quimioterapia com regressão total do edema facial.

Comentários Finais: O otorrinolaringologista deve estar atento para a existência dos linfomas entre as doenças nasossinusais, pois o diagnóstico precoce melhora a sobrevida na medida em que previne metástases, crescimento e destruição local.

Keywords

T-NK cells extranodal lymphoma - non-Hodgkin lymphoma - lymphoma - cells lymphoma

Palavras-chave

linfoma extranodal de células T-NK - linfoma não Hodgkin - linfoma - linfoma de células T
 

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