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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2020; 78(11): 738
DOI: 10.1590/0004-282X20200183
Editorial

Transient lesion in the splenium of the corpus callosum associated with COVID-19

Lesão transitória no esplênio do corpo caloso associada à COVID-19

Autoren

  • Felipe Araújo Andrade DE OLIVEIRA 

    1   Real Hospital Português de Beneficência de Pernambuco, Recife PE, Brazil.
    2   Universidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.

  • Tiago Feitosa Bastos DE MELO 

    1   Real Hospital Português de Beneficência de Pernambuco, Recife PE, Brazil.

  • Pedro Augusto Sampaio ROCHA-FILHO 

    2   Universidade Federal de Pernambuco, Centro de Ciências Médicas, Área Acadêmica de Neuropsiquiatria, Recife PE, Brazil.
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A healthy 40-year-old man experienced flu-like symptoms for four days and sought hospital care due to presenting progressive paresthesias in the extremities, mild headache, and visual turbidity. He had used only ivermectin and azithromycin. In the neurological examination, the patient presented a decrease in visual acuity in the left eye. The COVID-19 test using the nasal swab reverse transcription-polymerase chain reaction (RT-PCR) technique was positive. There were no metabolic disorders. The symptoms improved within seven days. Magnetic resonance imaging (MRI) demonstrated an ovoid lesion in the splenium of the corpus callosum with fluid-attenuated inversion recovery (FLAIR) hyperintensity, restricted diffusion and no gadolinium enhancement ([Figure 1]), which disappeared in a follow-up MRI one month later ([Figure 2]). Transient lesions of the splenium of the corpus callosum can be caused by other viruses[1],[2], but to our knowledge this is the first report of association with COVID-19[3],[4],[5].

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Figure 1 Magnetic resonance imaging demonstrating an ovoid lesion in the splenium of the corpus callosum with fluid-attenuated inversion recovery hyperintensity (A) and restricted diffusion (B, C).
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Figure 2 Follow-up magnetic resonance imaging one month later demonstrating complete resolution of the lesion in fluid-attenuated inversion recovery (A) and diffusion (B, C).

Authors’ contribution:

FAAO: conceptualization, data curation, investigation, writing of original draft, review & editing of final version. TFBM: conceptualization, data curation & investigation. PASRF: writing of original draft, review & editing of final version.




Publikationsverlauf

Eingereicht: 09. September 2020

Angenommen: 14. November 2020

Artikel online veröffentlicht:
07. Juni 2023

© 2020. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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