Effects of Comorbid Fibromyalgia Syndrome on activities of daily living in multiple sclerosis patients

ABSTRACT

Objective: To investigate the frequency of Comorbid Fibromyalgia Syndrome and its effects on quality of life and activities of daily living without any known psychiatric problem (schizophrenia or bipolar disorder) or severe disability, other than depression, in patients with multiple sclerosis, which is known to be a chronic disease in young adults. Methods: The study included 103 patients diagnosed with multiple sclerosis, following McDonald criteria, who had relapsing remitting disease. The Fibromyalgia Impact Questionnaire, Beck Anxiety Inventory, Beck Depression Inventory, Pittsburgh Sleep Quality Index, Fatigue Severity Scale, and Multiple Sclerosis Quality of Life-54 were applied for all patients. Results were analyzed using statistical methods. Results: Mean age was 35.04±8.72 years in the study population. The Expanded Disability Status Scale (EDSS) score was 2.21±0.93. Comorbid Fibromyalgia Syndrome was detected in 20 patients (19.4%). The mean score of Multiple Sclerosis Quality of Life-54 was found to be significantly higher in multiple sclerosis patients with Comorbid Fibromyalgia Syndrome when compared to those without it (34.80±9.14 versus 71.67±13.95; p<0.05). Conclusion: These results indicate that increased frequency of Comorbid Fibromyalgia Syndrome in multiple sclerosis causes worsening in activities of daily living and quality of life, delayed diagnosis, disability progression, and increased admission rates. Questioning and appropriately managing Comorbid Fibromyalgia Syndrome in clinical practice are important to improve the quality of life in multiple sclerosis patients.

RESUMEN

Objetivo: Investigar la frecuencia del Síndrome de Fibromialgia Comórbido y sus efectos sobre la calidad de vida y las actividades cotidianas sin problemas psiquiátricos conocidos o discapacidad grave en pacientes con esclerosis múltiple, que se conoce como una enfermedad crónica en adultos jóvenes. Métodos: El estudio incluyó a 103 pacientes diagnosticados con esclerosis múltiple, según los criterios de McDonald, que tenían enfermedad remitente recurrente. En todos los pacientes se completaron: el Cuestionario de Impacto de Fibromialgia, el Inventario de Ansiedad de Beck, el Inventario de Depresión de Beck, el Índice de Calidad del Sueño de Pittsburgh, la Escala de Gravedad de Fatiga y la Calidad de Vida de la Esclerosis Múltiple-54. Los resultados se analizaron mediante métodos estadísticos. Resultados: La edad media fue de 35,04±8,72 años en la población de estudio. La puntuación de la Expanded Disability Status Scale (EDSS) fue de 2,21±0,93. Se detectó el Síndrome de Fibromialgia Comórbido en 20 pacientes (19,4%). Se encontró que la puntuación media de la Calidad de Vida de la Esclerosis Múltiple-54 era significativamente más alta en pacientes de esclerosis múltiple con Síndrome de Fibromialgia Comórbido en comparación con aquellos sin él (34,80±9,14 versus 71,67±13,95; p<0,05). Conclusión: Esos resultados indican que el aumento de la frecuencia del Síndrome de Fibromialgia Comórbido en la esclerosis múltiple provoca empeoramiento de las actividades cotidianas y la calidad de vida, diagnóstico tardío, progresión de la discapacidad y mayores tasas de admisión. Cuestionar y manejar adecuadamente el Síndrome de Fibromialgia Comórbido en la práctica clínica son importantes para mejorar la calidad de vida en pacientes con esclerosis múltiple.

Keywords:

Fibromyalgia - Quality of Life - Activities of Daily Living - Fatigue

Palabras clave:

Fibromialgia - Calidad de Vida - Actividades Cotidianas - Fatiga

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