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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(11): 863-868
DOI: 10.1590/0004-282X20160141
ARTICLE

Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters

Depressão e sexualidade na síndrome fibromiálgica: achados clínicos e correlação com parâmetros hematológicos
Bruna Alves
1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, São Paulo SP, Brasil;
2   Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil;
,
Telma M Zakka
2   Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil;
,
Manoel J. Teixeira
2   Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil;
,
Helena H. Kaziyama
2   Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil;
,
Jose T. T. Siqueira
3   Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Grupo de Dor Orofacial, São Paulo SP, Brasil.
,
Silvia R. D. T. Siqueira
1   Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, São Paulo SP, Brasil;
2   Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil;
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ABSTRACT

Fibromyalgia (FM) is characterized by chronic pain and comorbidities.

Objective To investigate sexuality and depression in women with FM compared with controls and to correlate the findings with hematological parameters.

Methods 33 women with FM and 19 healthy women were included and evaluated with the following instruments: Female Sexual Function Index, Beck Inventory, Visual Analogue Scale, medical history and laboratory exams.

Results The prevalence of sexual dysfunction (P = 0.007) and depression (P < 0.001) were higher in the study group than in the control group; they were positively correlated (P = 0.023). The study group showed lower serum concentrations of testosterone, free T4, antinuclear factor, and lower blood hemoglobin and hematocrit.

Conclusions FM was associated with high scores of sexual dysfunction and depression, and there were correlations with hematological parameters. We suggest the involvement of immune-inflammatory mediators and FM, which need further investigation to understand their role in FM syndrome and its comorbidities.

RESUMO

Fibromialgia (FS) é caracterizada por dor e comorbidades.

Objetivo investigar depressão e sexualidade em mulheres com FS comparadas a controles, e correlacionar os achados com parâmetros hematológicos.

Métodos 33 mulheres com FS e 19 controles saudáveis foram incluídas e avaliadas através dos seguintes instrumentos: Índice de Função Feminina Sexual, Inventário de Beck, escala visual analógica, história médica e exames laboratoriais.

Resultados A prevalência de disfunção sexual (P = 0,007) e depressão (P < 0,001) foram maiores no grupo de estudo do que nos controles; também houve correlação positiva (P = 0,023). O grupo de estudo apresentou menor concentração sérica de testosterona, T4 livre, fator antinuclear e menos concentração de hemoglobina e hematócrito.

Conclusões A FS associou-se com altos índices de disfunção sexual e depressão, e houve correlação com os parâmetros hematológicos estudados. Sugere-se o envolvimento de mediadores imuno-inflamatórios na FS, que necessita de maior investigação para a compreensão dos mecanismos tanto na FS e quanto em suas comorbidades.

fibromyalgia - depression - sexuality - hematologic tests
fibromialgia - depressão - sexualidade - testes hematológicos


Publication History

Received: 08 April 2016

Accepted: 12 July 2016

Article published online:
06 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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