Presence or absence of cognitive complaints in Parkinson’s disease: mood disorder or anosognosia?

Pollyanna Celso F Castro; Camila Catherine Aquino; André C. Felício; Flávia Doná; Leonardo M. I. Medeiros; Sçnia M. C.A Silva; Henrique Ballalai Ferraz; Paulo Henrique F Bertolucci; Vanderci Borges

doi:10.1590/0004-282X20160060

Arquivos de Neuro-Psiquiatria, Table of Contents

CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(06): 439-444
DOI: 10.1590/0004-282X20160060

ARTICLE

Presence or absence of cognitive complaints in Parkinson’s disease: mood disorder or anosognosia?

Presença ou ausência de queixas cognitivas na doença de Parkinson: transtorno de humor ou anosognosia?

Pollyanna Celso F Castro

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

²Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;

,

Camila Catherine Aquino

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

²Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;

,

André C. Felício

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

²Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;

,

Flávia Doná

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

⁴Universidade Anhanguera de São Paulo, Programa de Mestrado em Reabilitação do Equilíbrio Corporal e Inclusão Social, São Paulo SP, Brasil.

,

Leonardo M. I. Medeiros

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

,

Sçnia M. C.A Silva

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

,

Henrique Ballalai Ferraz

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

,

Paulo Henrique F Bertolucci

²Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;

³Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Doenças Neurodegenerativas, São Paulo SP, Brasil;

,

Vanderci Borges

¹Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;

› Author Affiliations

Abstract

ABSTRACT

We intended to evaluate whether non-demented Parkinsons’s disease (PD) patients, with or without subjective cognitive complaint, demonstrate differences between them and in comparison to controls concerning cognitive performance and mood. We evaluated 77 subjects between 30 and 70 years, divided as follows: PD without cognitive complaints (n = 31), PD with cognitive complaints (n = 21) and controls (n = 25). We applied the following tests: SCOPA-Cog, Trail Making Test-B, Phonemic Fluency, Clock Drawing Test, Boston Naming Test, Neuropsychiatric Inventory, Hospital Anxiety and Depression Scale (HADS) and Beck Depression Inventory. PD without complaints presented lower total score on Scales for outcome of Parkinson’s disease-cognition as compared to controls (p = 0.048). PD with complaints group showed higher scores on HADS (p = 0.011). PD without complaints group showed poorer cognitive performance compared to controls, but was similar to the PD with complaints group. Moreover, this group was different from the PD without complaints and control groups concerning mood.

RESUMO

Avaliar se pacientes com doença de Parkinson (DP) sem demência, com ou sem queixa cognitiva subjetiva, demonstram diferenças entre eles e comparativamente aos controles relativos a desempenho cognitivo e humor. Avaliados 77 indivíduos entre 30 e 70 anos: PD sem queixas cognitivas (n = 31), PD com queixas cognitivas (n = 21) e controles (n = 25). Testes aplicados: SCOPA-cognição, Trail Making Test-B, Fluência Fonêmica, Teste do Relógio, Teste Nominativo de Boston, Inventário Neuropsiquiátrico, Escala Hospitalar de Depressão e Ansiedade (HADS)e Inventário de Depressão de Beck. PD sem queixas apresentaram menor pontuação total na SCOPA-cognição, comparativamente aos controles (p = 0,048). Por outro lado, PD com queixas apresentaram maior pontuação no HADS (p = 0,011) em comparação aos controles. O grupo PD sem queixas mostrou pior desempenho cognitivo em comparação aos controles, mas foi semelhante ao PD com queixas. Este grupo foi diferente dos grupos PD sem queixas e controle em relação ao humor.

Parkinson disease - cognition - dementia - depression - anxiety

doença de Parkinson - cognição - demência - depressão - ansiedade

Full Text

References

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