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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(06): 439-444
DOI: 10.1590/0004-282X20160060
ARTICLE

Presence or absence of cognitive complaints in Parkinson’s disease: mood disorder or anosognosia?

Presença ou ausência de queixas cognitivas na doença de Parkinson: transtorno de humor ou anosognosia?
Pollyanna Celso F Castro
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
2   Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;
,
Camila Catherine Aquino
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
2   Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;
,
André C. Felício
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
2   Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;
,
Flávia Doná
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
4   Universidade Anhanguera de São Paulo, Programa de Mestrado em Reabilitação do Equilíbrio Corporal e Inclusão Social, São Paulo SP, Brasil.
,
Leonardo M. I. Medeiros
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
,
Sçnia M. C.A Silva
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
,
Henrique Ballalai Ferraz
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
,
Paulo Henrique F Bertolucci
2   Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo SP, Brasil;
3   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Doenças Neurodegenerativas, São Paulo SP, Brasil;
,
Vanderci Borges
1   Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Transtornos do Movimento, São Paulo SP, Brasil;
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ABSTRACT

We intended to evaluate whether non-demented Parkinsons’s disease (PD) patients, with or without subjective cognitive complaint, demonstrate differences between them and in comparison to controls concerning cognitive performance and mood. We evaluated 77 subjects between 30 and 70 years, divided as follows: PD without cognitive complaints (n = 31), PD with cognitive complaints (n = 21) and controls (n = 25). We applied the following tests: SCOPA-Cog, Trail Making Test-B, Phonemic Fluency, Clock Drawing Test, Boston Naming Test, Neuropsychiatric Inventory, Hospital Anxiety and Depression Scale (HADS) and Beck Depression Inventory. PD without complaints presented lower total score on Scales for outcome of Parkinson’s disease-cognition as compared to controls (p = 0.048). PD with complaints group showed higher scores on HADS (p = 0.011). PD without complaints group showed poorer cognitive performance compared to controls, but was similar to the PD with complaints group. Moreover, this group was different from the PD without complaints and control groups concerning mood.

RESUMO

Avaliar se pacientes com doença de Parkinson (DP) sem demência, com ou sem queixa cognitiva subjetiva, demonstram diferenças entre eles e comparativamente aos controles relativos a desempenho cognitivo e humor. Avaliados 77 indivíduos entre 30 e 70 anos: PD sem queixas cognitivas (n = 31), PD com queixas cognitivas (n = 21) e controles (n = 25). Testes aplicados: SCOPA-cognição, Trail Making Test-B, Fluência Fonêmica, Teste do Relógio, Teste Nominativo de Boston, Inventário Neuropsiquiátrico, Escala Hospitalar de Depressão e Ansiedade (HADS)e Inventário de Depressão de Beck. PD sem queixas apresentaram menor pontuação total na SCOPA-cognição, comparativamente aos controles (p = 0,048). Por outro lado, PD com queixas apresentaram maior pontuação no HADS (p = 0,011) em comparação aos controles. O grupo PD sem queixas mostrou pior desempenho cognitivo em comparação aos controles, mas foi semelhante ao PD com queixas. Este grupo foi diferente dos grupos PD sem queixas e controle em relação ao humor.

Parkinson disease - cognition - dementia - depression - anxiety
doença de Parkinson - cognição - demência - depressão - ansiedade

Support:

Support: This study was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).




Publikationsverlauf

Eingereicht: 10. Oktober 2015

Angenommen: 02. März 2016

Artikel online veröffentlicht:
06. September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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