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CC BY-NC-ND 4.0 · Arq Neuropsiquiatr 2016; 74(04): 351-353
DOI: 10.1590/0004-282X20160029
HISTORICAL NOTES

On the centenary of the birth of Francis H. C. Crick – from physics to genetics and neuroscience

O centenário de nascimento de Francis H.C. Crick – da física para a genética e a neurociência
Hélio A. G. Teive
Universidade Federal do Paraná,Hospital das Clínicas, Serviço de Neurologia,CuritibaPR,Brazil.
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ABSTRACT

The year 2016 marks the centenary of the birth of Francis Crick (1916–2004), who made outstanding contributions to genetics and neuroscience. In 1953, in a collaborative study, Francis Crick and James Watson discovered the DNA double helix, and in 1962 they and Maurice Wilkins were awarded the Noble Prize in Physiology or Medicine. Crick subsequently became very interested in neuroscience, particularly consciousness and its relationship to the claustrum, a small gray matter structure between the insula and putamen.

RESUMO

O ano de 2016 é o centenário de nascimento de Francis Crick (1916–2004), físico, biólogo e neurocientista, cujas contribuições para a genética e a neurociência foram magníficas. Crick, em um estudo colaborativo com Watson, descobriu a estrutura molecular do DNA (dupla hélice) em 1953, e em 1962 ambos receberam o prêmio Nobel de Fisiologia ou Medicina, junto com Wilkins. Após Crick tornou-se muito interessado na área de neurociência, particularmente no estudo da consciência, e a sua relação com o claustrum, uma pequena estrutura de substância cinzenta localizada entre a ínsula e o putame.

crick - double helix - Nobel prize - consciousness - claustrum
crick - dupla hélice - prêmio Nobel - consciência - claustrum


Publication History

Received: 02 January 2016

Accepted: 07 January 2016

Article published online:
06 September 2023

© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Olby R. Francis Crick: hunter of life’s secrets. New York: Cold Spring Harbor Laboratory; 2009.
  • 2 Watson J. Crick F. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature. 1953;171(4356):737-8.
  • 3 Edelstein LR, Denaro FJ. The claustrum: a historical review of its anatomy, physiology, cytochemistry and functional significance. Cell Mol Biol (Noisy-le-grand). 2004;50(6):675-702. doi:10.1170/T558
  • 4 Mathur BN. The claustrum in review. Front Syst Neurosci. 2014;8:48. doi:10.3389/fnsys.2014.00048
  • 5 Goll Y, Atlan G, Citri A. Attention: the claustrum. Trends Neurosci. 2015;38(8):486-95. doi:10.1016/j.tins.2015.05
  • 6 Stevens CF. Consciousness: crick and the claustrum. Nature. 2005;435(7045):1040-1. doi:10.1038/4351040a
  • 7 Crick F, Koch C, Kreiman G, Fried I. Consciousness and neurosurgery. Neurosurgery. 2004;55(2):273-81. doi:10.1227/01.NEU.0000129279.26534.76
  • 8 Stiefel KM, Merrifield A, Holcombe AO. The claustrum’s proposed role in consciousness is supported by the effect and target localization of Salvia divinorum. Front Integr Neurosci. 2014;8:20. doi:10.3389/fnint.2014.00020
  • 9 Crick FC, Koch C. What is the function of the claustrum? Philos Trans R Soc Lond B Biol Sci. 2005;360(1458):1271-9. doi:10.1098/rstb.2005.1661
  • 10 Knight J. From DNA to consciousness: Crick’s legacy. Nature. 2004;430(7000):597. doi:10.1038/430597a