From disease to noninvasive intracranial monitoring

ABSTRACT

Professor Sérgio Mascarenhas was a Brazilian researcher with a vast legacy. His work paved the way for new research possibilities by consolidating the use of innovation and transdisciplinary science. In Medicine, he proposed changes to what had previously been well-accepted concepts, and his contributions have influenced medical practices. Although many authors consider intracranial pressure (ICP) as an unrivaled variable for monitoring and diagnosis of many diseases, its clinical applicability is still the subject of debate in the literature because of the difficulty in standardizing protocols. Mascarenhas's research and the creation of a device for noninvasive monitoring of intracranial compliance are discussed and are shown to have led to the creation of Brain4care, a start-up, and a new perspective on the debate on ICP monitoring.

RESUMO

O professor Sérgio Mascarenhas foi um pesquisador com vasto legado. Seu trabalho abriu caminho para novas possibilidades de pesquisa, consolidando o uso da inovação e da ciência transdisciplinar. Na Medicina, ele propôs mudanças no que antes eram conceitos bem-aceitos, e suas contribuições influenciaram a prática médica. Embora muitos autores considerem a pressão intracraniana (PIC) uma variável incomparável para o monitoramento e o diagnóstico de uma série de doenças, sua aplicabilidade clínica ainda é motivo de debate na literatura pela dificuldade de padronização de protocolos. A pesquisa do Professor Mascarenhas e a criação de um dispositivo para o monitoramento não invasivo da complacência intracraniana levaram à criação do Brain4care, uma start-up, e a uma nova perspectiva sobre o debate do monitoramento da PIC.

Keywords:

Hydrocephalus, Normal Pressure - Parkinson Disease - Monitoring

Palavras-chave:

Hidrocefalia de Pressão Normal - Doença de Parkinson - Monitoramento

Authors’ contributions:

CMF and SCVK: conceptualization, investigation, methodology, validation, visualization, writing—original draft, and writing—review and editing; MCR and FAM: validation, visualization, and writing—original draft; GRM and GF: validation, visualization, writing—original draft, writing—review and editing; AKM: validation, visualization, writing—original draft, and writing—review and editing and supervision.

Publication History

Received: 26 July 2021

Accepted: 12 November 2021

Article published online:
06 February 2023

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