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Thromb Haemost 2016; 116(06): 1041-1049
DOI: 10.1160/TH16-02-0151
Coagulation and Fibrinolysis
Schattauer Publishers Schattauer

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels

Weihua Zhang
1   Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
1   Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
,
Fredrik Jernerén
3   Department of Pharmacology, University of Oxford, Oxford, UK
,
Benjamin C. Lehne
1   Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
,
Ming-Huei Chen
4   Population Sciences Branch, National Heart, Lung, Blood Institute, National Institutes of Health, Framingham, Massachusetts, USA
,
Robert N. Luben
5   Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
,
Carole Johnston
3   Department of Pharmacology, University of Oxford, Oxford, UK
,
Amany Elshorbagy
3   Department of Pharmacology, University of Oxford, Oxford, UK
6   Department of Physiology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt
,
Ruben N. Eppinga
7   Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
8   Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
,
William R. Scott
1   Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
9   National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK
,
Elizabeth Adeyeye
2   Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, UK
10   Faculty of Medicine, Imperial College London, South Kensington Campus, London, UK
,
James Scott
9   National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK
,
Rainer H. Böger
11   Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
Kay-Tee Khaw
5   Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
,
Pim van der Harst
7   Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
8   Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
,
Nicholas J. Wareham
12   Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK
,
Ramachandran S. Vasan
13   Section of Preventive Medicine and Epidemiology and Cardiology, Boston University School of Medicine, Boston, Massachusetts, USA
14   Boston University and National Heart, Lung & Blood Institute’s Framingham Heart Study, Framingham Massachusetts, USA
,
John C. Chambers
1   Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
2   Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, UK
15   Imperial College Healthcare NHS Trust, London, UK
,
Helga Refsum
3   Department of Pharmacology, University of Oxford, Oxford, UK
16   Department of Nutrition, Institute of Basic Medical Science, Faculty of Medicine, University of Oslo, Oslo, Norway
,
Jaspal S. Kooner
2   Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, UK
9   National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK
15   Imperial College Healthcare NHS Trust, London, UK
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