Influence of membrane composition on the enhancement of factor VIIa/tissue factor activity by magnesium ions

 

^* Current address: Department of Cell Biology, Harvard Medical School, Boston, MA, USA.

• References

• 1 Sunnerhagen M, Forsén S, Hoffrén AM. et al. Structure of the Ca2+-free GLA domain sheds light on membrane binding of blood coagulation proteins.. Nat Struct Biol 1995; 2: 504-509.
• 2 Furie B, Furie BC. The molecular basis of blood coagulation.. Cell 1988; 53: 505-518.
• 3 Wang S, McDonnell EH, Sedor FA. et al. pH effects on measurements of ionized calcium and ionized magnesium in blood.. Arch Pathol Lab Med 2002; 126: 947-950.
• 4 Sekiya F, Yamashita T, Atoda H. et al. Regulation of the tertiary structure and function of coagulation factor IX by magnesium(II) ions.. J Biol Chem 1995; 270: 14325-14331.
• 5 Sekiya F, Yoshida M, Yamashita T. et al. Magnesium(II) is a crucial constituent of the blood coagulation cascade – Potentiation of coagulant activities of factor IX by Mg2+ ions.. J Biol Chem 1996; 271: 8541-8544.
• 6 van den Besselaar AMHP. Magnesium and manganese ions accelerate tissue factor-induced coagulation independently of factor IX.. Blood Coagul Fibrinolysis 2002; 13: 19-23.
• 7 Bajaj SP, Schmidt AE, Agah S. et al. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192–193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.. J Biol Chem 2006; 281: 24873-24888.
• 8 Persson E, Ostergaard A. Mg2+ binding to the Gla domain of factor X influences the interaction with tissue factor.. J Thromb Haemost 2007; 5: 1977-1978.
• 9 Persson E. Protein disulfide isomerase has no stimulatory chaperone effect on factor X activation by factor VIIa-soluble tissue factor.. Thromb Res 2008; 123: 171-176.
• 10 Vadivel K, Agah S, Messer AS. et al. Structural and functional studies of -carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium.. J Mol Biol 2013; 425: 1961-1981.
• 11 Vadivel K, Bajaj SP. Structural biology of factor VIIa/tissue factor initiated coagulation.. Front Biosci 2012; 17: 2476-2494.
• 12 Prendergast FG, Mann KG. Differentiation of metal ion-induced transitions of prothrombin fragment 1.. J Biol Chem 1977; 252: 840-850.
• 13 Neuenschwander PF, Bianco-Fisher E, Rezaie AR. et al. Phosphatidylethanolamine augments factor VIIa-tissue factor activity: enhancement of sensitivity to phosphatidylserine.. Biochemistry 1995; 34: 13988-13993.
• 14 Tavoosi N, Davis-Harrison RL, Pogorelov TV. et al. Molecular determinants of phospholipid synergy in blood clotting.. J Biol Chem 2011; 286: 23247-23253.
• 15 Tavoosi N, Smith SA, Davis-Harrison RL. et al. Factor VII and protein C are phosphatidic acid-binding proteins.. Biochemistry. 2013 in Press.
• 16 Shaw AW, Pureza VS, Sligar SG. et al. The local phospholipid environment modulates the activation of blood clotting.. J Biol Chem 2007; 282: 6556-6563.
• 17 Neuenschwander PF, Morrissey JH. Roles of the membrane-interactive regions of factor VIIa and tissue factor. The factor VIIa Gla domain is dispensable for binding to tissue factor but important for activation of factor X.. J Biol Chem 1994; 269: 8007-8013.
• 18 de Courcy B, Pedersen LG, Parisel O. et al. Understanding selectivity of hard and soft metal cations within biological systems using the subvalence concept. I. Application to blood coagulation: direct cation-protein electronic effects vs. indirect interactions through water networks.. J Chem Theory Comput 2010; 6: 1048-1063.
• 19 Ohkubo YZ, Tajkhorshid E. Distinct structural and adhesive roles of Ca2+ in membrane binding of blood coagulation factors.. Structure 2008; 16: 72-81.