Seeing is believing: An update on modalities to image inflammation in vivo

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• References

• 1 Medzhitov R. Origin and physiological roles of inflammation. Nature 2008; 454: 428-435.
• 2 Nathan C. Points of control in inflammation. Nature 2002; 420: 846-852.
• 3 Ley K, Laudanna C, Cybulsky MI. et al. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 2007; 7: 678-689.
• 4 Bellido-Martin L, Chen V, Jasuja R. et al. Imaging fibrin formation and platelet and endothelial cell activation in vivo. Thromb Haemost 2011; 105: 776-782.
• 5 Gautam N, Olofsson AM, Herwald H. et al. Heparin-binding protein (HBP/CAP37): a missing link in neutrophil-evoked alteration of vascular permeability. Nat Med 2001; 7: 1123-1127.
• 6 Kenne E, Lindbom L. Imaging inflammatory plasma leakage in vivo. Thromb Haemost 2011; 105: 783-789.
• 7 Constantinescu A, Spaan JA, Arkenbout EK. et al. Degradation of the endothelial glycocalyx is associated with chylomicron leakage in mouse cremaster muscle microcirculation. Thromb Haemost 2011; 105: 790-801.
• 8 Nourshargh S, Hordijk PL, Sixt M. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol 2010; 11: 366-378.
• 9 Megens TA, Kemmerich K, Pyta J. et al. Intravital imaging of phagocyte recruitment. Thromb Haemost 2011; 105: 802-810.
• 10 Drechsler M, Megens RT, van Zandvoort M. et al. Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis. Circulation 2010; 122: 1837-1845.
• 11 Soehnlein O, Lindbom L. Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol 2010; 10: 427-439.
• 12 Soehnlein O, Zernecke A, Eriksson EE. et al. Neutrophil secretion products pave the way for inflammatory monocytes. Blood 2008; 112: 1461-1471.
• 13 Gray C, Loynes CA, Whyte MK. et al. Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish. Thromb Haemost 2011; 105: 811-819.
• 14 Mause SF, Weber C. Intrusion through the fragile back door: immature plaque microvessels as entry portals for leukocytes and erythrocytes in atherosclerosis. J Am Coll Cardiol 2009; 53: 1528-1531.
• 15 Megens RT, oude Egbrink MG, Merkx M. et al. Two-photon microscopy on vital carotid arteries: imaging the relationship between collagen and inflammatory cells in atherosclerotic plaques. J Biomed Opt 2008; 13: 044022.
• 16 Zagorchev L, Mulligan-Kehoe MJ. Advances in imaging angiogenesis and inflammation in atherosclerosis. Thromb Haemost 2011; 105: 820-827.
• 17 Quillard T, Croce K, Jaffer FA. et al. Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thromb Haemost 2011; 105: 828-836.