PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAα1) prevents the passage of tissuetype plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity

Benoit D. Roussel; Yannick Hommet; Richard Macrez; Torsten Schulz; Karl-Uwe Petersen; Vincent Berezowski; Roméo Cecchelli; Carine Ali; Denis Vivien

doi:10.1160/TH09-02-0114

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2009; 102(03): 606-608
DOI: 10.1160/TH09-02-0114

Letters to the Editor

Schattauer GmbH

PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAα1) prevents the passage of tissuetype plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity

Benoit D. Roussel^*

¹INSERM, INSERM U919, Serine Proteases and Pathophysiology of the neurovascular Unit, CNRS, UMR CNRS 6232 CINAPs “Center for Imaging Neurosciences and Applications to Pathologies”, Cyceron, Caen Cedex, F-14074 France; University of Caen Basse-Normandie, Caen Cedex, France

,

Yannick Hommet^*

¹INSERM, INSERM U919, Serine Proteases and Pathophysiology of the neurovascular Unit, CNRS, UMR CNRS 6232 CINAPs “Center for Imaging Neurosciences and Applications to Pathologies”, Cyceron, Caen Cedex, F-14074 France; University of Caen Basse-Normandie, Caen Cedex, France

,

Richard Macrez

¹INSERM, INSERM U919, Serine Proteases and Pathophysiology of the neurovascular Unit, CNRS, UMR CNRS 6232 CINAPs “Center for Imaging Neurosciences and Applications to Pathologies”, Cyceron, Caen Cedex, F-14074 France; University of Caen Basse-Normandie, Caen Cedex, France

,

Torsten Schulz

²PAION Deutschland GmbH, Aachen, Germany

,

Karl-Uwe Petersen

²PAION Deutschland GmbH, Aachen, Germany

,

Vincent Berezowski

³Laboratoire de Physiopathologie de la Barrière Hémato-Encéphalique, EA 2465, IFR114-IMPRT, Université d’Artois, Faculté des Sciences Jean Perrin, France

,

Roméo Cecchelli

³Laboratoire de Physiopathologie de la Barrière Hémato-Encéphalique, EA 2465, IFR114-IMPRT, Université d’Artois, Faculté des Sciences Jean Perrin, France

,

Carine Ali

¹INSERM, INSERM U919, Serine Proteases and Pathophysiology of the neurovascular Unit, CNRS, UMR CNRS 6232 CINAPs “Center for Imaging Neurosciences and Applications to Pathologies”, Cyceron, Caen Cedex, F-14074 France; University of Caen Basse-Normandie, Caen Cedex, France

,

Denis Vivien

¹INSERM, INSERM U919, Serine Proteases and Pathophysiology of the neurovascular Unit, CNRS, UMR CNRS 6232 CINAPs “Center for Imaging Neurosciences and Applications to Pathologies”, Cyceron, Caen Cedex, F-14074 France; University of Caen Basse-Normandie, Caen Cedex, France

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References

References
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