Summary
Venous thromboembolism (VTE) has long been considered a disease of secondary importance
among Asians because of its perceived low prevalence. We studied the prevalence and
patterns of deep venous thrombosis (DVT) among hospitalised patients in our tertiary
referral centre. Primary and secondary DVT prevalence among hospitalised patients
was 0.453%, a significant rise from reported rates of 0.079% and 0.158% in 1989–1990
and 1996–1997, respectively. Malignancies and orthopaedic surgery were the most common
risk factors for DVT. Further comparisons with the two earlier Singaporean studies
showed no changes in the gender and ethnic background of patients but a higher proportion
of elderly patients (>80 years) was recorded in the current study (11.7% vs. 7.0%,
p = 0.04). Statistically significant increases were found in all medical and surgical
disciplines except among obstetrics and gynaecology patients. Orthopaedic patients
had the highest increase in DVT rates between the 1989–1990 and 2002–2003 periods
(0.082% vs. 0.96%, p<0.01). Doppler ultrasound scans performed increased from approximately
one per 100 admissions in 1996–1997 to one per 30 admissions in 2002–2003. The significant
increase in period prevalence of DVT among hospitalised patients in Singapore could
be accounted by methodologic differences between comparative studies, an increase
in proportion of elderly patients and most importantly, a possible shift in perception
of the importance of VTE among Asians, resulting in a higher index of suspicion and
lower threshold for performing diagnostic tests.
Keywords
Venous thrombosis - Asians - prevalence