Hyperhomocysteinaemia, thrombosis and pernicious anaemia

• References

• 1 den Heijer M, Koster T, Blom HJ. et al. Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med 1996; 334: 759-62.
• 2 Graham IM, Daly LE, Refsum HM. et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA 1997; 277: 1775-81.
• 3 Mudd SH, Skovby F, Levy HL. et al. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet 1985; 37: 1-31.
• 4 Selhub J, Jacques PF, Wilson PW. et al. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993; 270: 2693-8.
• 5 Toh BH, van Driel IR, Gleeson PA. Pernicious anemia. N Engl J Med 1998; 338: 995.
• 6 Fernandez-Miranda C, Yebra MYebra, Ribera CCasado. et al. Venous thromboembolism and hyperhomocysteinemia as first manifestation of pernicious anemia. Rev Clin Esp 2005; 205: 489-92.
• 7 Caldera A. Pulmonary embolism in a patient with pernicious anemia and hyperhomocysteinemia. Chest 2002; 122: 1487-8.
• 8 Kharchafi A, Oualim Z, Amezyane T. et al. Biermer’s disease and venous thrombosis. Report of two cases. Rev Med Interne 2002; 23: 563-6.
• 9 Savage DG, Lindenbaum J, Stabler SP. et al. Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. Am J Med 1995; 99: 444-6.
• 10 Riba R, Nicolaou A, Troxler M. et al. Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels. Atherosclerosis 2004; 175: 69-75.
• 11 Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 1998; 338: 1042-50.
• 12 Andres E, Perrin AE, Noel E. et al. Vitamin B12 deficiency-induced moderate hyperhomocysteinemia and venous thromboembolism. Ann Med Interne 2002; 153: 483-4.
• 13 Marie I, Levesque H, Le Cam-Duchez V. et al. Mesenteric venous thrombosis revealing both factor II G20212A mutation and hyperhomocysteinemia related to pernicious anemia. Gastroenterology 2000; 118: 237-8.
• 14 Gradman WS, Daniel J, Miller B. et al. M. Homocysteine-associated acute mesenteric artery occlusion treated with thrombectomy and bowel resection. Ann Vasc Surg 2001; 15: 247-50.