Angiographic documentation of the efficacy of recombinant activated factor VII (NovoSeven) to control diffuse bleeding in major trauma

Bart Van Der Schueren; Frank Hammer; Franck Verschuren; Philippe Hantson; Véronique Deneys; Cedric Hermans

doi:10.1160/TH05-06-1327

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2005; 94(06): 1327-1328
DOI: 10.1160/TH05-06-1327

Case Report

Schattauer GmbH

Angiographic documentation of the efficacy of recombinant activated factor VII (NovoSeven) to control diffuse bleeding in major trauma

Bart Van Der Schueren

¹ Haemostasis and Thrombosis Unit, 1Department of Haematology

,

Frank Hammer

² Department of Radiology and Diagnostic Imaging, Emergency and

,

Franck Verschuren

³ Intensive Care Department, Haemostasis Laboratory

,

Philippe Hantson

³ Intensive Care Department, Haemostasis Laboratory

,

Véronique Deneys

⁴ Department of Biological Chemistry, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, Brussels, Belgium

,

Cedric Hermans

¹ Haemostasis and Thrombosis Unit, 1Department of Haematology

› Author Affiliations

Abstract

Full Text

References

References
1 Kenet G, Walden R, Eldad A. et al Treatment of traumatic bleeding with recombinant factor VIIa. Lancet 1999; 354: 1879.
2 Goodnough LT, Lublin DM, Zhang L. et al Transfusion medicine service policies for recombinant factor VIIa administration. Transfusion 2004; 44: 1325-31.
3 Grounds M. Recombinant factor VIIa (rFVIIa) and its use in severe bleeding in surgery and trauma: a review. Blood Rev 2003; 17: S11-21.
4 Dutton RP, McCunn M, Hyder M. et al Factor VIIa for correction of traumatic coagulopathy. J Trauma 2004; 57: 709-19.
5 Eikelboom JW, Bird R, Blythe D. et al Recombinant activated factor VII for the treatment of lifethreatening haemorrhage. Blood Coagul Fibrinolysis 2003; 14: 713-7.
6 Boffard KD, Riou B, Warren B. et al NovoSeven Trauma Study Group. Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma 2005; 59: 8-15 discussion 15–8.
7 Levi M, Peters M, Buller HR. Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: a systematic review. Crit Care Med 2005; 33: 883-90.
8 Ahonen J, Jokela R. Recombinant factor VIIa for life-threatening post-partum haemorrhage. Br J Anaesth 2005; 94: 592-5.
9 Goodnough LT, Lublin DM, Zhang L. et al Transfusion medicine service policies for recombinant factor VIIa administration. Transfusion 2004; 44: 1325-31.
10 Martinowitz U, Michaelson M. Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: a report by the Israeli Multidisciplinary rFVIIa Task Force. J Thromb Haemost 2005; 3: 640-8.