Synlett 2008(10): 1532-1536  
DOI: 10.1055/s-2008-1078411
LETTER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of the Central Tryptophan-Leucine Residue of Celogentin C

Julien Michaux*a, Pascal Retailleaub, Jean-Marc Campagne*c
a Institut de Chimie des Substances Naturelles, Avenue de la Terrasse, 91198 Gif sur Yvette, France
b Service de Cristallochimie, Institut de Chimie des Substances Naturelles, Avenue de la Terrasse, 91198 Gif sur Yvette, France
c Institut Charles Gerhardt Montpellier, ENSCM, 8 rue de l"Ecole Normale, 34296 Montpellier, France
e-Mail: jean-marc.campagne@enscm.fr;
Further Information

Publication History

Received 6 March 2008
Publication Date:
16 May 2008 (eFirst)

Abstract

The synthesis of the central tryptophan residue of celogentin C is described featuring a Pd-catalyzed imine/enamine Heck-type reaction, a Pd-catalyzed Suzuki coupling, and an asymmetric Rh-catalyzed hydrogenation.