FeCl₃/TMSCl: An Effective Catalytic System for the Conjugate Addition of Sodium p-Toluenesulfinate to α,β-Enones

Abstract

A new protocol for the β-sulfonation of α,β-unsaturated carbonyl compounds is described. The method employs FeCl₃ as catalyst and TMSCl as additive for conjugate addition of sodium p-toluenesulfinate to enones.

β-sulfonyl ketones - conjugate addition - α,β-unsaturated carbonyl compounds - iron(III) chloride - trimethylsilyl chloride

References and Notes

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