Endoscopy 2008; 40(10): 862-867
DOI: 10.1055/s-2008-1077588
DDW highlights

© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic diagnosis and treatment of upper gastrointestinal tumors

M.  Polkowski1
  • 1Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Further Information

Publication History

Publication Date:
30 September 2008 (online)

Introduction

At the 2008 Digestive Diseases Week (DDW) that took place in San Diego, California, a substantial amount of research on advanced endoscopic techniques for diagnosing and treating tumors of the upper gastrointestinal tract was presented ([Fig. 1]). In this review, we discuss the final or interim findings of 21 selected papers that focused on new developments in the diagnosis of cancer and precancerous lesions [1] [2] [3] [4] [5] [6], endotherapy for early cancer and precancerous lesions [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18], and endotherapy of advanced cancer [19] [20] [21].

Fig. 1 One hundred seventy-nine abstracts on endoscopic diagnosis and treatment of upper gastrointestinal tumors presented at Digestive Diseases Week 2008 organized according to topic. ESD, endoscopic submucosal dissection; EMR, endoscopic mucosal resection.

References

  • 1 McCallum A L, Macpherson M, Jenkin J T. et al . Autofluorescence assessment in the surveillance of Barrett’s oesophagus: a randomised trial comparing standard 4 quadrant biopsy and AF directed biopsy [abstract].  Gastroenterology. 2008;  134 A63
  • 2 Dunbar K B, Montgomery E A, Okolo P, Canto M I. Confocal laser endomicroscopy in Barrett’s esophagus and associated neoplasia: a prospective randomized controlled crossover trial [abstract].  Gastrointest Endosc. 2008;  67 AB97-AB98
  • 3 Badreddine R J, Wang K K, Prasad G A. et al . Confocal laser microscopy (CLM) guided endoscopic mucosal resection in Barrett’s esophagus with high grade dysplasia [abstract].  Gastrointest Endosc. 2008;  67 AB179
  • 4 Wolfsen H C, Achem S R, DeVault K R, Wallace M B. Detection of dysplasia in Barrett’s esophagus using narrow band imaging: prospective, controlled tandem endoscopy study dysplasia detection in patients with Barrett’s esophagus [abstract].  Gastroenterology. 2008;  134 A38
  • 5 Dellon E S, Madanick R D, Edmundowicz S A. et al . Biopsy yield of dysplastic Barrett’s esophagus based on location within the Barrett’s segment [abstract].  Gastroenterology. 2008;  134 A433-A434
  • 6 Bansal A, Rastogi A, Curvers W L. et al . Inter-observer variability in the assessment of NBI mucosal and vascular patterns in Barrett’s esophagus (BE) patients: a multi-center study [abstract].  Gastroenterology. 2008;  134 A724
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  • 8 Gondrie J J, Seewald S, Pouw R E. et al . Stepwise radical endoscopic resection for complete removal of Barrett’s esophagus with early neoplasia: an international multicenter study [abstract].  Gastrointest Endosc. 2008;  67 AB175-AB176
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  • 10 Greenwald B D, Horwhat J D, Abrams J A. et al . Endoscopic cryotherapy ablation is safe and well-tolerated in Barrett’s esophagus, esophageal dysplasia, and esophageal cancer [abstract].  Gastrointest Endosc. 2008;  67 AB76
  • 11 Dumot J A, Vargo J J, Zuccaro G. et al . Results of cryospray ablation for esophageal high grade dysplasia (HGD) and intramucosal cancer (IMCA) in high risk non-surgical patients [abstract].  Gastrointest Endosc. 2008;  67 AB176
  • 12 Canto M I, Dunbar K B, Okolo P. et al . Low flow CO2-cryotherapy for high risk Barrett’s esophagus (BE) patients with high grade dysplasia and early adenocarcinoma: a pilot trial of feasibility and safety [abstract].  Gastrointest Endosc. 2008;  67 AB179-AB180
  • 13 Chung I K, Kim H J, Lee S H. et al . Therapeutic outcome in 1000 cases of endoscopic submucosal dissection (ESD) for early gastric neoplasms; Korean ESD Study Group (KESG) multi-center study [abstract].  Gastrointest Endosc. 2008;  67 AB94
  • 14 Kojima E, Tashiro K, Tajima T. et al . Usefulness of endoscopic submucocal dissection versus gastrectomy in elderly patients with early gastric cancer [abstract].  Gastrointest Endosc. 2008;  67 AB282
  • 15 Deprez P H, Yeung R C, Aouattah T. et al . Prospective randomized comparison between EMR and ESD for endoscopic removal of superficial esophageal cancer [abstract].  Gastrointest Endosc. 2008;  67 AB187
  • 16 Ishihara R, Iishi H, Uedo N. et al . Which endoscopic resection method is best to treat small esophageal cancers? [abstract].  Gastrointest Endosc. 2008;  67 AB95
  • 17 Moon S H, Choi K D, Song H J. et al . Prognosis of patients with early gastric cancer who underwent additional gastrectomy after incomplete endoscopic mucosal resection [abstract].  Gastrointest Endosc. 2008;  67 AB95
  • 18 Fukase K, Kato M, Kikuchi S, Asaka M. Eradication of Helicobacter pylori for the incidence of metachronous gastric cancer after endoscopic resection [abstract].  Gastroenterology. 2008;  134 A148
  • 19 Castaño R, Alvarez O A, Lopera J. et al . Endoscopic stenting versus surgical gastrojejunostomy for palliation of malignant gastroduodenal obstruction [abstract].  Gastrointest Endosc. 2008;  67 AB151
  • 20 Van Hooft J, Uitdehaag M, Bruno M. et al . Final results of a prospective multicentre, clinical study on the efficacy of the new Wallflex enteral stent in malignant gastric outlet obstruction (Duoflex) [abstract].  Gastrointest Endosc. 2008;  67 AB141
  • 21 Eickhoff A, Kaehler G F, Meessen D. et al . Palliation in patients with malignant gastric outlet obstruction with the newly designed Wallflex duodenal stent: first data of a multicenter, prospective trial [abstract].  Gastrointest Endosc. 2008;  67 AB137-AB138
  • 22 Abrams J A, Lightdale C J, Singhal A V. et al . Predictors of adequate biopsy sampling in patients with Barrett’s esophagus: analysis of a national community-based gastrointestinal pathology database [abstract].  Gastroenterology. 2008;  134 A79
  • 23 Curvers W L, Böhmer C J, Mallant-Hent R C. et al . Detailed inspection of the mucosal morphology in Barrett’s esophagus by narrow band imaging has no additional value over inspection with high-resolution endoscopy: an international inter-observer study using expert and non-expert endoscopists [abstract].  Gastroenterology. 2008;  134 A192
  • 24 Alvarez Herrero L, Curvers W L, Bansal A. et al . Interobserver agreement of a simplified classification system of mucosal morphology using narrow band imaging in Barrett’s esophagus: an international multi-center study [abstract].  Gastrointest Endosc. 2008;  67 AB132
  • 25 Peters F P, Kara M A, Curvers W L. et al . Multiband mucosectomy for endoscopic resection of Barrett’s esophagus: feasibility study with matched historical controls.  Eur J Gastroenterol Hepatol. 2007;  19 311-315
  • 26 Pouw R E, Gondrie J J, Van Vilsteren F G. et al . Stepwise circumferential and focal radiofrequency ablation of Barrett’s esophagus with high-grade dysplasia or intramucosal cancer [abstract].  Gastroenterology. 2008;  134 A844
  • 27 Bumgarner J M, Panjehpour M, Long M. et al . Comparison of catheter-based radiofrequency ablation and photodynamic therapy for Barrett’s esophagus [abstract].  Gastroenterology. 2008;  134 A436
  • 28 Probst A, Messmann H. Endoscopic submucosal dissection (ESD) of large mucosal and submucosal lesions in the GI tract – rising experience and learning curve in a European center [abstract].  Gastrointest Endosc. 2008;  67 AB295-AB296
  • 29 Yamaguchi Y, Nakamura K, Toki M. et al . Resection area of 15 mm as dividing line for choosing strip biopsy or endoscopic submucosal dissection for mucosal gastric neoplasm [abstract].  Gastrointest Endosc. 2008;  67 AB145
  • 30 Kato M, Asaka M, Ono S. et al . Eradication of Helicobacter pylori for primary gastric cancer and secondary gastric cancer after endoscopic mucosal resection.  J Gastroenterol. 2007;  42 Suppl 17 16-20
  • 31 Van Hooft J, Mutignani M, Repici A. et al . First data on the palliative treatment of patients with malignant gastric outlet obstruction using the WallFlex enteral stent: a retrospective multicenter study.  Endoscopy. 2007;  39 434-439

M. PolkowskiMD 

Department of Gastroenterology and Hepatology
Medical Center for Postgraduate Education
M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology

Roentgena 5
02-781 Warsaw
Poland

Fax: +48-22-5463035

Email: m.polkowski@coi.waw.pl

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