Synthesis 2008(18): 2991-2995  
DOI: 10.1055/s-2008-1067244
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Palladium-Mediated Direct Synthesis of N-Substituted 4-Methyl- and 4-Ethylisoquinolone Derivatives

Krishna C. Majumdar*, Santanu Chakravorty, Krishanu Ray
Department of Chemistry, University of Kalyani, Kalyani 741235, WB, India
Fax: +91(33)25828282; e-Mail: kcm_ku@yahoo.co.in;
Further Information

Publication History

Received 14 February 2008
Publication Date:
22 August 2008 (online)

Abstract

N-Substituted 4-methyl- and 4-ethylisoquinolone derivatives are prepared from different N-allylbenzamide derivatives in a single step through a ligand-free palladium-mediated intramolecular Heck cyclization.

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Majumdar, K. C.; Chattopadhaya, B.; Nath, S. Tetrahedron Lett., in press.

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Majumdar K. C., Debnath P., Taher A., Pal A. K.; Can. J. Chem., in press.