© Georg Thieme Verlag KG Stuttgart · New York
Familial Occurrence of Intracranial Aneurysms in Childhood:
A Case Report and Review of the Literature
19 March 2008 (online)
This report describes three individuals belonging to one family, who were affected with ruptured intracranial aneurysms (IAs) at a rather young age, 4, 15 and 23 years respectively. Familial IAs at this young age have not been described before.
The evidence for a developmental, eventually inherited origin of familial IA in childhood is discussed with reference to the low occurrence of non-familial IA in childhood, IA-features in non-familial cases (localisation, multiplicity, size) and the association with (other) congenital malformations in the 0-5 years group.
Intracranial aneurysms - Congenital malformations - Hereditary defects - Familial - Childhood