Neuropediatrics 1987; 18(4): 210-212
DOI: 10.1055/s-2008-1052482
© Georg Thieme Verlag KG Stuttgart · New York

The Effect of ACTH on Plastic Synapses in the Developing Mouse Brain

A.  Tateno1 , N.  Koya1 , T.  Aoki1 , F.  Nasu2
  • 1Department of Pediatrics, Ohashi Hospital, Toho University School of Medicine, Ohashi 2-16-7, Meguro-ku, Tokyo 153, Japan
  • 2Department of Anatomy, Toho University School of Medicine, Oomorinishi 5-21-16, Oota-ku, Tokyo, Japan
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Publication History

Publication Date:
15 May 2008 (online)

Abstract

We studied the effect of ACTH on plastic synapses in the hippocampal gyrus of the developing mouse brain. Examination of ethanolic phosphotungustic acid stained synaptic junctions revealed no obvious differences between the ACTH-treated brains and controls qualitatively and quantitatively. Therefore, ACTH may not adversely affect the plastic synapses in the developing mouse brain.