Int J Sports Med 1981; 02(2): 101-105
DOI: 10.1055/s-2008-1034591
© Georg Thieme Verlag Stuttgart · New York

Structural Alterations of Liver Parenchyma Induced by Anabolic Steroids*

C. Stang-Voss, H.-J.  Appell
  • Institut für Experimentelle Morphologie der Deutschen Sporthochschule Köln
* This article is cordially dedicated to Professor Dr. Jochen Staubesand on the occasion of his 60th birthday.
Further Information

Publication History

Publication Date:
14 March 2008 (online)

Abstract

The long-term effects of an anabolic steroid (Dianabol) on the liver of motor-active mice was investigated. The pathologic changes occurring are due to cholestasis, peliosis hepatis, and diffuse hepatitis. It was assumed that a pathogenic relationship between cholestasis, peliosis, and cirrhosis exists. Neoplasms seldom occurred, but it was suggested that anabolic steroids do not primarily induce the formation of liver tumors.