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Int J Sports Med 1981; 02(2): 101-105
DOI: 10.1055/s-2008-1034591
DOI: 10.1055/s-2008-1034591
Structural Alterations of Liver Parenchyma Induced by Anabolic Steroids*
* This article is cordially dedicated to Professor Dr. Jochen Staubesand on the occasion of his 60th birthday.Further Information
Publication History
Publication Date:
14 March 2008 (online)
Abstract
The long-term effects of an anabolic steroid (Dianabol) on the liver of motor-active mice was investigated. The pathologic changes occurring are due to cholestasis, peliosis hepatis, and diffuse hepatitis. It was assumed that a pathogenic relationship between cholestasis, peliosis, and cirrhosis exists. Neoplasms seldom occurred, but it was suggested that anabolic steroids do not primarily induce the formation of liver tumors.
Key words
anabolic steroids - liver - ultrastructure - mouse