Kontralaterale Beeinflussung transitorisch evozierter otoakustischer Emissionen*

Zusammenfassung

Hintergrund: Der Einfluß kontralateral applizierten weißen Rauschens auf transitorisch evozierte oto-akustische Emissionen (TEOAE) wird von verschiedenen Autoren in Hinblick auf einen Beitrag cochleärer Efferenzen diskutiert. Methoden: In den vorliegeneden Untersuchungen erfolgte eine ipsilaterale Registrierung der TEOAE unter Verwendung verschiedener Clickpegel bei gleichzeitiger kontralateraler Stimulation mit weißem Rauschen verschiedener Pegel. In einer weiteren Meßreihe wurde das Verhalten der TEOAE nach kontralateraler Stimulation untersucht. Ergebnisse: Für wachsende kontralaterale Stimulation nahm der Pegel der TEOAE ab, gleichzeitig stieg der Rauschuntergrund an. Die TEOAE erreichten nach Beendigung der kontralateralen Stimulation den Ausgangszustand innerhalb weniger Minuten, demgegenüber lag auch nach 10 min noch ein erhöhter Rauschuntergrund vor. Schlußfolgerungen: Die Suppression der TEOAE bei gleichzeitigem Ansteigen des Rauschuntergrundes während kontralateraler Stimulation läßt sich schlüssiger auf eine Änderung der Übertragungseigenschaften des Mittelohres als auf die Aktivität der cochleären Efferenzen zurückführen. Weitere Einflüsse, wie Veränderungen des vegetativen Systems, Überhören und Maskierungseffekte werden diskutiert.

Summary

Background: In recent publications the influence of contralateral white noise on transient evoked otoacoustic emissions (TEOAE) is discussed with regard on contributions of the efferent auditory system. Methods: In the present study the effects have been investigated with regards to middle-ear muscles, efferents and cross hearing. TEOAE to monaural 40-80 dB SPLclicks were recorded in normal-hearing adults under simultaneous presentation of 20-60dB SPL broadband noise to the contralateral ear. Control runs were performed before, during a short break of, and after contralateral stimulation. The control run before contralateral stimulation was used as a reference. Results: Decrease in TEOAE, and increase in accompanying noise floor, were found to follow the contralateral stimulation. In particular a 1-3dB decrease was found for contralateral noise levels of 40 and 60 dB SPL, even though the readings at 60 dB only were statistically significant (paired-samples t test, p = 0.05). For both TEOAE and noise floor no systematic dependence on dick intensity was seen. The control runs during temporary break and after contralateral noise revealed an increase in both TEOAE and noise floor. As a rule, the TEOAE adapted to the reference within 2-3 min following the cessation of contralateral stimulation, whereas the increased noise floor level was still noted after 10 min. Conclusions: Traditionally, suppressing effects of contralateral stimulation on TEOAE have been attributed to cochlear efferents (CEs). Occasionally, the middle-ear muscle and cross hearing involvement have been considered as well. Substantially, the present results and findings of other workers are inconsistent with the basic knowledge of CE functioning: (i) The decrease in TEOAE under contralateral stimulation is in conflict with an increase in cochlear microphonics and summating potentials observed during activation of CEs; (ii) contralateral suppression of TEOAE exhibited no significant dependence on the test-stimulus level while the CEs are known to be efficient in the range of the low signal intensities only, and (IM) acoustic activation of the CEs can hardly be expected to reach levels sufficient to influence the TEOAE mechanism. The present findings, i.e. decrease in TEOAE and increase in noise floor level, can more reasonably be explained as being mainly attributable to activation of the middle-ear muscles.

Schlüsselwörter

TEOAE - Kontralaterale Beeinflussung - Mittelohrmuskeln - Efferente Innervation - Cochleäre Efferenzen - Stapediusreflex

Keywords

TEOAE - Noise floor - Contralateral influence - Cochlear efferents - Olivocochlear bundle - Middle-ear muscles