Horm Metab Res 1980; 12(6): 240-242
DOI: 10.1055/s-2007-996257

© Georg Thieme Verlag, Stuttgart · New York

Increased Gastrin Release in Chronic Calcifying Pancreatitis and in Chronic Alcoholism

M. J. Treffot, R. Laugier, A. Bretholz, M. Voirol, H. Sarles
  • Unité de Recherches de Pathologie Digestive, Marseille, France
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Publication History



Publication Date:
14 March 2008 (online)


Plasma gastrin levels were measured by radioimmunoassay before and after a test meal associated with 40 ml ethanol in 21 patients with chronic calcifying pancreatitis, in 10 apparently normal subjects drinking since at least 5 years 100 g alcohol a day, in 14 subjects presenting hepatic alcoholic cirrhosis and in 18 apparently normal non alcoholic controls. Post-stimulation gastrin concentrations were higher in chronic pancreatitis patients or in normal alcoholics (peak post-stimulation value: 74 ± 41 and 74 ± 43 pg/ml respectively) than in cirrhotics or non alcoholic controls (45 ± 26 and 41 ± 15 pg/ml respectively) (m ± SD).