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DOI: 10.1055/s-2007-992165
© Sonntag Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG
Apocynum venetum L. - von der traditionellen Droge zum modernen Phytopharmakon
Publikationsverlauf
Publikationsdatum:
18. Juni 2008 (online)

Zusammenfassung
Das Venezianische Hundsgift (Apocynum venetum L.,) wird seit Hunderten von Jahren in China als traditionelles Phytopharmakon zur Behandlung von Bluthochdruck, Nierenentzündungen und Neurasthenie verwendet. In den letzten zwei Jahrzehnten wurden dem mehrjährigen krautartigen Gewächs durch intensive Forschungsarbeiten weitere Wirkungen wie antioxidative, antidepressive, anxiolytische und lipidsenkende Eigenschaften zugesprochen. Dieser Artikel gibt einen kurzen Überblick über den aktuellen Stand der pharmazeutischen und pharmakologischen Forschung.
Summary
Apocynum venetum L., a traditional herbal drug with up-to-date pharmacological effects
The Venetian dogbane (Apocynum venetum L., Apocynaceae) has been used in traditional Eastern medicine for hundreds of years as a tea to treat high blood pressure, nephritis, and neurasthenia. A leaf extract of Apocynum venetum is rich in polyphenolic compounds such as flavonols, flavonoids, and caffeic acid derivatives, which are known to exhibit a variety of pharmacological activities. Intensive research in the past two decades has shown that the perennial shrub possesses many medicinal values including antioxidant, antidepressant, anxiolytic, and lipid-lowering properties. This review gives a brief overview of the current pharmaceutical and pharmacological research of Apocynum venetum.
Schlüsselwörter
Apocynum venetum - Apocynaceae - Hundsgift - Traditionelle Medizin - ZNS - antidepressiv - angstlösend - Pharmakologie
Key words
Apocynum venetum - Apocynaceae - dogbane - traditional medicine - CNS - antidepressant - anxiolytic - pharmacology
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Dr. Veronika Butterweck
Department of Pharmaceutics
College of Pharmacy
University of Florida
POBox 100494
Gainesville, FL 32608
USA
eMail: butterwk@cop.ufl.edu