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Semin Reprod Med 2007; 25(6): 476-482
DOI: 10.1055/s-2007-991045
© Thieme Medical Publishers

The Influence of Hydrosalpinx on Markers of Endometrial Receptivity

Ricardo Francalacci Savaris1 , 2 , Linda C. Giudice2
  • 1Departamento de Ginecologia e Obstetricia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
  • 2Department of Obstetrics and Gynecology, University of California, San Francisco, California
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Publication History

Publication Date:
25 October 2007 (online)

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ABSTRACT

Hydrosalpinx is a common condition among women of reproductive age. It is related to low pregnancy rates in the settings of in vitro fertilization-embryo transfer programs. Such low rates are not yet well understood, and may be due to poor endometrial receptivity and abnormal expression of key molecules in the endometrium that are important for implantation. The available data on the inflammatory response, endometrial blood flow, integrins, leukemia inhibitory factor, matrix metalloproteinases, and homeobox gene A10 expression in the presence of hydrosalpinx are reviewed. In addition, the evidence for treatment options to improve pregnancy rates is also discussed.

KEYWORDS

Hydrosalpinx - endometrium

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Ricardo Francalacci SavarisM.D. 

Department of Obstetrics and Gynecology, University of San Francisco

505 Parnassus Ave., M1496, Box 0.132, San Francisco, CA 94143-013

Email: rsavaris@hcpa.ufrgs.br

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