A Mild and Environmentally Benign Oxidation of Thiols to Disulfides

Masayuki Kirihara; Yasutaka Asai; Shiho Ogawa; Takuya Noguchi; Akihiko Hatano; Yoshiro Hirai

doi:10.1055/s-2007-990800

SHORTPAPER

A Mild and Environmentally Benign Oxidation of Thiols to Disulfides

Masayuki Kirihara*^a, Yasutaka Asai^a, Shiho Ogawa^a, Takuya Noguchi^a,b, Akihiko Hatano^a, Yoshiro Hirai^b
^a Department of Materials and Life Science, Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555, Japan
Fax: +81(538)450110; e-Mail: kirihara@ms.sist.ac.jp;
^b Department of Chemistry, Faculty of Science, Toyama University, 3190 Gofuku, Toyama 930-8555, Japan

Abstract

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Abstract

Thiols were effectively oxidized into disulfides by reacting with hydrogen peroxide in the presence of a catalytic amount of iodide ion or iodine.

Key words

thiol - disulfide - oxidative coupling - hydrogen peroxide - iodide catalyst

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References

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