Correlation of contrast-enhanced harmonic sonography and microvessel density of renal cell carcinoma

Y. Chen; Y. Hao; N. Wu; Y. Ran

doi:10.1055/s-2007-989128

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Ultraschall Med 2007; 28 - P_14_10
DOI: 10.1055/s-2007-989128

Correlation of contrast-enhanced harmonic sonography and microvessel density of renal cell carcinoma

Y Chen ¹, Y Hao ¹, N Wu ¹, Y Ran ²

¹Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Diagnostic Department, Beijing, China
²Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Cellular biology and molecular biology, Beijing, China

Congress Abstract

Objectives: The purpose of this study was to correlate the imaging findings of renal cell carcinoma on contrast-enhanced harmonic sonography with microvessel density and histopathological grades.

Methods: A total of 47 patients with 47 renal cell carcinomas were enrolled in this study prospectively. The enhancement extent of RCC, microvessel density, and histopathological grades were analyzed statistically.

Results: A significant positive correlation was observed between MVD (3.0˜58.7, mean: 40.9±12.6) and the enhancement extent (2.28˜29.36dB, mean 14.94±6.14dB) of RCC (r=0.782, p<0.0001), and also between MVD and histopathological grades (G1=20, G2=16, G3=11) of RCC (r=0.319, p=0.029).

Conclusions: The assessment of tumour enhancement extent on contrast-enhanced harmonic sonography is of prognostic significance for patients with RCC.