Planta Med 2007; 73 - P_188
DOI: 10.1055/s-2007-986969

Antibacterial and anticandidal activity studies on Sonchus erzincanicus Matthews

D Yiğit 1, N Yiğit 2, U Özgen 3, HG Sevindik 3, AE Aktaş 4
  • 1Erzincan University, Faculty of Education, Erzincan, 24030, Turkey
  • 2Atatürk University, Health Services Vocational Training School, Medical Laboratory Program, Erzurum, 25070, Turkey
  • 3Atatürk University, Faculty of Pharmacy, Department of Pharmacognosy, Erzurum, 25240, Turkey
  • 4Atatürk University, Faculty of Medicine, Microbiology and Clinical Microbiology Department, Erzurum, 25240, Turkey

Sonchus erzincanicus (Compositae) is an endemic species for Turkey [1]. Six Sonchus species grow in Turkey and are known as „sütlük, kuzu gevreği, eşek marulu“ in Turkey [2]. It has been found that some Sonchus species contain sesquiterpene lactone glucosides, flavonoids, triterpenes and steroids [3,4]. In this study, the antibacterial and anticandidal activity of aerial parts of Sonchus erzincanicus Matthews methanol extract and fractions (CHCl3, EtOAc, aqueous) prepared from methanol extract were evaluated against clinical bacterial and Candida strains.

Tested organism

Zone of inhibition (mm)

Water

MeOH

EtOAc

CHCl 3

Escherichia coli

10

15

13

14

Staphylococcus aureus

-

10

-

5

Enterobacter aerogenes

-

10

-

-

Candida albicans

-

13

12

13

Candida glabrata

-

10

10

-

Candida parapsilosis

-

-

10

10

Ampicillin (10µg) >19–10mm sensitive Amphotericin B (10µg) >15–10mm sensitive

References: [1] Matthews, V.A. (1975) Sonchus L. Flora of Turkey and the East Aegean Islands, University Pres. Edinburgh, Volume: 5, pp. 690–696 (edited by Davis, P. H.). [2] Akartürk, R. (2001) Şifalı Bitkiler Flora ve Sağlığımız, Orman Genel Müdürlüğü Mensupları Yardımlaşma Vakfı (in Turkish). [3] Helal A.M. et al. (2000) Phytochemistry 53(4), 473–477. [4] Devkota, K.P. (2005). Ph. D. Thesis, Research Institute Of Chemistry/University of Karachi.