Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml
Planta Med 2007; 73 - P_085
DOI: 10.1055/s-2007-986867
DOI: 10.1055/s-2007-986867
A novel isoflavonoid from Millettia puguensis
From the roots of Millettia puguensis (Leguminosae), a novel isoflavonoid (1), 2'-methoxy-4',5'-methylenedioxy-7,8-[2-(1-methylethenyl)furo]isoflavone, and four known compounds, i.e., lupeol, (-)-maackiain (2), 6,7-dimethoxy-3',4'-methylenedioxyisoflavone (3) and 7,2'-dimethoxy-4',5'-methylenedioxyisoflavone were isolated and identified by 1H-, 13C-NMR and mass spectroscopy. All compounds were evaluated for their antiprotozoal and cytotoxic activities, but only a moderate antileishmanial activity was observed for compound 3 (IC50 32µM against Leishmania infantum), and a moderate cytotoxicity for compound 2 (IC50 43µM on MRC-5 cells) [1].
References: 1. Kapingu et al. (2006) Planta Med. 72: 1341–1343