Deutsche Zeitschrift für Onkologie 2007; 39(4): 178-183
DOI: 10.1055/s-2007-986021
Praxis
Behandlungsprobleme
© Karl F. Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Weihrauch in der Therapie von hirneigenen Tumoren und Hirnödemen

R. Charles Fernando, Hüseyin Sahinbas
Further Information

Publication History

Publication Date:
20 December 2007 (online)

Zusammenfassung

Das Harz des Weihrauchbaums enthält therapeutisch wirksame Boswelliasäuren (BA), die selektiv die Leukotriensynthese hemmen. Dadurch wird die Entzündungskaskade ohne nennenswerte Nebenwirkungen unterbrochen. Auch bei Langzeiteinnahme von Weihrauch bleibt die Initialwirkung erhalten. Indikationen für eine Therapie mit Weihrauch sind alle chronisch-entzündlichen und allergischen Erkrankungen. Die komplementäre Onkologie ist ein möglicher Einsatzbereich. Forschungsergebnisse zeigen, dass BA Topoisomerasen hemmen und somit die Apoptose von malignen Zellen einleiten.

Summary

The resin of the frankincense tree contains therapeutically effective boswellic acids (BA). Four predominant BA selectively inhibit the synthesis of Leucotrienes (LT). A variety of chronic diseases is predominantly accompanied by excessive formation of LT and hence support and prolong the inflammatory process. Starting from the arachidonic acid, the inflammatory and pain cascade is interrupted without significant side effects. Even on the basis of long-term intake, the initial effects are maintained. Indications for a frankincense therapy are all chronic inflammatory and allergic diseases. A different pathway of activity involves the Inhibition of topoisomerases I and II via frankincense. In vitro studies show that at higher concentrations BA inhibited the proliferation of tumour cells, possibly by inducing programmed cell death (apoptosis) of malignant cells. The frankincense genus from northeast Africa (Boswellia carterii), in particular Eritrea, delivers an outstanding quality of the pharmaceutical drug and is free from heavy metals and preservatives. Based on clinical experience, the treatment of patients having tumor induced oedema derived from brain tumors (astrocytoma, glioblastoma) and brain metastases with frankincense (boscari®), have revealed impressive results. At higher concentrations (3 × 4 - 5 cps.) the effectiveness of anti-oedemic acrtivity and complience is observed. Peri-tumoural brain oedemas are generally suppressed employing glucocorticosteroides that can cause substantial side effects lead to further chronic illnesses especially after long-term application.

Literatur

Korrespondenzadresse

Dr. rer. nat. R. Charles Fernando

Hauptstr. 141

69488 Birkenau

Email: info@olibanum-bv.com

Dr. med. Hüseyin Sahinbas

Universität Witten/Herdecke
Grönemeyer Institut

Universitätsstr. 140

44799 Bochum

Email: sahinbas@microtherapy.de

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