Berberis vulgaris L. - die Berberitze

Zusammenfassung

Berberis vulgaris, die Berberitze, aus der Familie der Berberidaceae, ist in Mitteleuropa und in anderen Regionen der Erde beheimatet. Alle Pflanzenteile werden seit Langem in der traditionellen Medizin verwendet, insbesondere im Mittelalter bei entzündlichen Erkrankungen, Verdauungsstörungen, Leber-, Milz- und Gallenblasenbeschwerden und bei Infektionen. Pflanzenteile von B. vulgaris werden jedoch heute in Mitteleuropa - im Gegensatz zu anderen Kulturkreisen - im Wesentlichen nur noch in der Homöopathie eingesetzt. Relevante Inhaltsstoffe sind Alkaloide (insbesondere Berberin), die in der Stammrinde und in der Wurzeldroge in größerer Menge vorkommen. Mithilfe moderner Methoden konnten unter anderem antimikrobielle, antiinflammatorische und antirheumatische Wirkungen sowie antihypertensive Aktivitäten nachgewiesen werden.

Summary

Berberis vulgaris, the common barberry, from the Berberidaceae family, is indigenous to central Europe and other regions of the world. Since the Middle Ages, all parts of the plant are used in traditional medicine for the treatment of inflammations, gastrointestinal disorders, and disorders of the liver, the spleen and the bile as well as infectious diseases. Nowadays, however, the plant is used in Europe only in homoeopathic preparations in contrast to other cultures. The most prominent ingredients are alkaloids (especially berberine) present in considerable amounts mainly in the stem bark and the roots. The application of modern methods has led - amongst others - to the determination of the plant's antimicrobial, anti-inflammatory, anti-rheumatic and anti-hypertensive effects.

Berberis vulgaris L. - Berberidaceae - Berberitze - Berberin - Alkaloide - antimikrobiell - antiinflammatorisch - antihypertensiv

Berberis vulgaris L. - Berberidaceae - (common) barberry - berberine - alkaloids,

Literatur

• 1 Ahrendt LWA. Berberis and Mahonia. A taxonomic revision.  J Linn Soc. 1961;  57
• 2 Birdsall TC, Kelly GS. Berberine: Therapeutic potential of an alkaloid found in several medicinal plants.  Altern Med Rev. 1997;  2 94-103
• 3 Bonjar GHS. Anti yeast activity of some plants used in traditional herbal-medicine in Iran.  J Biol Sci. 2004;  4 212-215
• 4 Chandra P, Purohit AN. Berberine contents and alkaloid profile of Berberis species from different altitudes.  Biochem Syst Ecol. 1980;  8 379-380
• 5 Chandra P, Todaria NP. Maturation and ripening of three Berberis species from different altitudes.  Sci Hort. 1983;  19
• 6 Fata A, Rakhshandeh H, Berenji F, Jalalianfard A. Treatment of cutaneous leishmaniasis in murine model by alcoholic extract of Berberis vulgaris.  Iranian J Parasitol. 2006;  1 39-42
• 7 Fatehi M, Saleh TM, Fatehi-Hassanabad Z, Farrokhfal K. et al. . A pharmacological study on Berberis vulgaris fruit extract.  J Ethnopharmacol. 2005;  102 46-52
• 8 Fatehi-Hassanabad Z, Jafarzadeh M, Tarhini A, Fatehi M. The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats.  Phytother Res. 2005;  19 222-225
• 9 Fuchs L. New Kreüterbuch. Basel; 1543; Köln: Taschen 2001
• 10 Henderson GA, Hay GW. The carbohydrates of the leaves of common barberry (Berberis vulgaris). The extraction, fractionation and structural studies of selected non-cellulosic polysaccharides.  Carbohyd Res. 1972;  23 379-398
• 11 Ikram M. A review on the chemical and pharmacological aspects of genus Berberis.  Planta Med. 1975;  28 353-358
• 12 Ivanovska N, Philipov S. Study on the anti- inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids.  Int J Immunopharmacol. 1996;  18
• 13 Karimov A. Berberis alkaloids.  Chem Nat Comp. 1993;  29 481-506
• 14 Karimov A, Yusupov MM, Shakirov R. Berberis alkaloids. XV. Structure of bargustanine.  Chem Nat Comp. 1993;  29 44-47
• 15 Khamidov I, Telezhenetskaya MV, Karimov A. Berberis alkaloids. XXXIII. Investigations of the alkaloids of Berberis.  Chem Nat Comp. 1995;  31 503-504
• 16 Kim YD, Kim SH, Landrum LR. Taxonomic and phytogeographic implications from IST phylogeny in Berberis (Berberidaceae).  J Plant Res. 204;  117 175-182
• 17 Kreis W. Berberis. In: Hänsel R, Keller K, Rimpler H, Schneider G (Hrsg.): Hagers Handbuch der Pharmazeutischen Praxis. Berlin, Heidelberg, New York: Springer 1992: 480-497
• 18 Küpeli E, Kosar M, Yesilada E, Baser KHC, Baser C. A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species.  Life Sci. 2002;  72 645-657
• 19 Lonitzer A. Naturalis historiae opus novum. Frankfurt a.M.; 1551-1557, Monographie Oxyacantha (= Berberis)
• 20 Manolov P, Nikolov N, Markov M, Toneva M. Eksperimentalni prouchvaniia na Berberis vulgaris [Experimental studies on Berberis vulgaris].  Eksp Med Morfol. 1985;  24 41-45
• 21 Marek R, SecŠ#kárŠová P, Hulová D, Marek J. et al. . Palmatine and berberine isolation artifacts.  J Nat Prod. 2003;  66 481-486
• 42 Villinski JR, Dumas ER, Chai HB, Pezzuto JM. et al. .Comparison of antimicrobial activities and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis. [Posterbeitrag] 41. Jahrestagung der American Society of Pharmacognosy, Seattle 2000. (www.tomsofmain.com/downloads/pdf/ 2000
• 43 Villinski JR, Dumas ER, Chai HB, Pezzuto JM. et al. . Antibacterial activity and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis.  Pharm Biol. 2003;  41 551-557
• 44 Yesilada E, Küpeli E. Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats.  J Ethnopharmacol. 2002;  79 237-248
• 45 Yusopov MM, Karimov A, Lutfullin KL. Alkaloids of Berberis vulgaris. XII.  Chem Nat Comp. 1980;  726 128-129